Adeyanju, O., Nwanta, U., Shuaibu, Y., Hussaini, Y., . Adejoh, A. (2016). Effect of Acetylation on Physicochemical Characteristics of Cashew Exudate Gum(Anacardium occidentale).A Potential Excipient. test, 2(3), 74-77. doi: 10.18576/jpac/020311
O. Adeyanju; U. C. Nwanta; Y. Shuaibu; Y. Hussaini; A. I . Adejoh. "Effect of Acetylation on Physicochemical Characteristics of Cashew Exudate Gum(Anacardium occidentale).A Potential Excipient". test, 2, 3, 2016, 74-77. doi: 10.18576/jpac/020311
Adeyanju, O., Nwanta, U., Shuaibu, Y., Hussaini, Y., . Adejoh, A. (2016). 'Effect of Acetylation on Physicochemical Characteristics of Cashew Exudate Gum(Anacardium occidentale).A Potential Excipient', test, 2(3), pp. 74-77. doi: 10.18576/jpac/020311
Adeyanju, O., Nwanta, U., Shuaibu, Y., Hussaini, Y., . Adejoh, A. Effect of Acetylation on Physicochemical Characteristics of Cashew Exudate Gum(Anacardium occidentale).A Potential Excipient. test, 2016; 2(3): 74-77. doi: 10.18576/jpac/020311

Effect of Acetylation on Physicochemical Characteristics of Cashew Exudate Gum(Anacardium occidentale).A Potential Excipient

Journal of Pharmaceutical and Applied Chemistry
Volume 2, Issue 3, September 2016, Pages 74-77    PDF (403.6 K)
Document Type: Original Article
DOI: 10.18576/jpac/020311
Authors
O. Adeyanju1; U. C. Nwanta1; Y. Shuaibu2; Y. Hussaini3; A. I . Adejoh1
1Department of Chemistry, University of Jos, Jos, Nigeria.
2Department of General Studies, College of Administrative and Business Studies, Potiskum, Nigeria
3Department of Science Laboratory Technology, Federal College of Forestry, Jos, Nigeria.
Abstract
The modification discussed include the acetylation of cashew gum with acetic anhydride in the presence of sodium hydroxide. The resulting product was characterized by FTIR spectroscopy. Physicochemical characteristics such as solubility, viscosity and swelling index of the native cashew gum and acetylated cashew gum were also determined. The results showed that the acetylated gum had higher values of solubility, viscosity and swelling index as 113.40% at 80oC, 53.4cs and 49.54% respectively while the native gum had solubility viscosity and swelling index as 50.10% at 80oC,
20.20cs and 10.94% respectively. Chemical modification via acetylation increased the solubility, viscosity and swelling index of cashew gum. The experimental work provides enough evidence to exploit this natural biopolymer in food, textile and pharmaceutical industry, especially as an efficient alternative approach for the oral delivery of hydrophilic macromolecules.

Keywords
Cashew gum; Chemical modification; acetyl group; drug delivery
Statistics
Article View: 110
PDF Download: 82