Thirunarayanan, G. (2017). The In-vitro Antimicrobial and Antioxidant Activities of some Diels-Alder Diaryl Methanone Adducts. test, 3(1), 46-53. doi: 10.18576/jpac/030102
Ganesamoorthy Thirunarayanan. "The In-vitro Antimicrobial and Antioxidant Activities of some Diels-Alder Diaryl Methanone Adducts". test, 3, 1, 2017, 46-53. doi: 10.18576/jpac/030102
Thirunarayanan, G. (2017). 'The In-vitro Antimicrobial and Antioxidant Activities of some Diels-Alder Diaryl Methanone Adducts', test, 3(1), pp. 46-53. doi: 10.18576/jpac/030102
Thirunarayanan, G. The In-vitro Antimicrobial and Antioxidant Activities of some Diels-Alder Diaryl Methanone Adducts. test, 2017; 3(1): 46-53. doi: 10.18576/jpac/030102

The In-vitro Antimicrobial and Antioxidant Activities of some Diels-Alder Diaryl Methanone Adducts

Journal of Pharmaceutical and Applied Chemistry
Volume 3, Issue 1, January 2017, Pages 46-53    PDF (688.2 K)
Document Type: Original Article
DOI: 10.18576/jpac/030102
Author
Ganesamoorthy Thirunarayanan
Department of Chemistry, Annamalai University, Annamalainagar-608 002, India.
Abstract
The in-vitro antimicrobial and antioxidant activities of some 2-(9H-fluorene-2-yl)-3-(substituted phenyl)bicyclo [2.2.1]hept-5-ene-2-yl methanones by disc-diffusion as well as serial dilution against their microbial strains and DPPH radical scavenging activities. The titled substrates were synthesized by environmentally benign water mediated Diels-Alder reaction of 9H-2-fluorenyl chalcones and cyclopentadiene in good yields. Conclusion: The present results confirm the positive correlation between the acute phase response of inflammation and oxidative stress in non-diabetic and diabetic obese subjects.

Keywords
In-vitro antimicrobial activity; Antioxidant activity; Diels-Alder adduct; Environmentally benign reaction
Statistics
Article View: 57
PDF Download: 47