Primary Broncho-Pulmonary Cancer in Women: Epidemiological Study, Clinical-Pathological Study and Therapeutic Load. | ||
| Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology | ||
| Article 10, Volume 13, Issue 2, December 2021, Pages 129-141 PDF (930.5 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/eajbsc.2021.201908 | ||
| Authors | ||
| Haoud Khadidja1; Mellali Sarah2; Benbegdad Maroua1; Zenaidi Manel1 | ||
| 1Département de Biologie, Faculté des Sciences de la Nature et de la Vie, Université Djillai LIABES Sidi Bel Abbès | ||
| 2Département de Biologie, Institut des Sciences exactes et Sciences de la Nature et de la Vie, Centre universitaire Ahmad ZABANA, Relizane | ||
| Abstract | ||
| Introduction: Primary bronchial cancer in women is a major public health problem; its incidence has increased steadily over the past 20 years. Objective: The objective of this work was to analyze the epidemiological, clinical, therapeutic and prognostic characteristics of lung cancer in women in the region of Sidi Bel Abbés. Materials and methods: A descriptive retrospective study of 50 women diagnosed with primary lung cancer collected in the oncology and radiotherapy department of anti cancer centre between January 2008 and May 2019. Results: The average age of our patients was 64 years (±15,063). Respiratory symptoms were dominated by chest pain. The main risk factors were passive smoking (26% of cases), family history of cancer, hormonal factors, environmental factors, history of respiratory diseases. The most common histological type was adenocarcinoma (74% of cases), stages III and IV accounted for 95% of cases. The main metastatic locations were bone and cervical (23.8%). Treatment management was based mainly on chemotherapy (50% of cases), of which 19% were palliative. Discussion: Our results confirm that bronchial cancer in women is steadily increasing. Its risk factors are different from those of men. The dominant histological type in women was adenocarcinoma, which has a better prognosis, however, the diagnosis remains late, which explains the predominance of stages III and IV in women. Conclusion: The female primary broncho-pulmonary cancer has anatomopathological, hormonal and genetic peculiarities that characterize it, which should encourage us to apprehend it differently from the therapeutic strategies better for women | ||
| Keywords | ||
| Cancer; Bronchial; Primitive; Female; Sidi Bel Abbès | ||
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