Skin and Nasal Colonization with Methicillin Resistant Staphylococcus Aureus in Children with Atopic Dermatitis | ||
| Egyptian Journal of Medical Microbiology | ||
| Article 5, Volume 30, Issue 1, January 2021, Pages 39-44 PDF (330.9 K) | ||
| Document Type: New and original researches in the field of Microbiology. | ||
| Author | ||
| Tamer Mohamed Mahmoud* | ||
| Department of Medical Microbiology and Immunology, Faculty of Medicine, Sohag University | ||
| Abstract | ||
| Background: Atopic dermatitis (AD) is a chronic inflammatory skin disease with multifactorial etiologies, Staphylococcus aureus (S.aureus) and methicillin-resistant S.aureus (MRSA) that naturally colonize skin and nose are prevalent among children with AD. Objectives: was to determine the prevalence of S.aureus and MRSA colonization of skin lesions and nose of AD children. Methodology: 40 children diagnosed as AD from Dermatology Clinic of Najran Armed Forces Hospital, Saudi Arabia, were included in the study; separate swabs from skin lesions & nose of each AD patient were tested for S.aureus and MRSA colonization using the conventional culture based Vitek 2 system and the molecular BD Max MRSA XT assay. Results: Using the conventional Vitek 2 system, the prevalence of skin and nasal colonization with S.aureus in AD patients were 25% and 30% respectively while skin and nasal colonization with MRSA were 7.5% and 7.5% respectively, the BD Max MRSA XT assay identified correctly S.aureus with overall 96 % sensitivity, 100 % specificity and 98 % diagnostic accuracy and identified 100 % of MRSA strains. Conclusion: The increase in prevalence of skin and nasal colonization with S.aureus and MRSA among AD children raises the concern about importance of the accurate and rapid molecular diagnostic techniques for preventing the potential risk of MRSA transmission | ||
| Keywords | ||
| Atopic Dermatitis; Methicillin resistant S.aureus; Vitek 2 system; BD Max assay | ||
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