Multiple Sclerosis and Vitamin D: Is there a Link in the Multifactorial Model? | ||
| Suez Canal University Medical Journal | ||
| Editorial, Volume 25, Issue 1, March 2022, Pages 1-12 PDF (320.09 K) | ||
| DOI: 10.21608/scumj.2022.204002 | ||
| Author | ||
| Asmaa K Abdelmaogood* | ||
| Department of Clinical & Chemical Pathology, Faculty of Medicine, Suez Canal University, Ismailia Egypt; Research fellow, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK. | ||
| Abstract | ||
| MS is a rare neurodegenerative disease with an immunopathological background. Although, it has a rather low global prevalence, it can be considered among one of the most common youth disabling disorders that are not related to trauma. It is also classified as a complex disease with many susceptibility genes incriminated in its etiology and prognosis. In addition, several well identified and extensively studied environmental factors are implicated as vitamin D metabolism & ultraviolet B (UVB) exposure, Epstein Barr virus (EBV) infection, smoking and morbid obesity. The infamous relationship between Vitamin D and MS has been an area of extensive research in many aspects; pathophysiology, disease course, prognosis and even response to treatment. | ||
| Keywords | ||
| Autoimmune demyelinating diseases; 1; 25 dihydroxy vitamin D3; Autoimmune diseases | ||
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