Khalifa, S., Marzouk, M., Metwaly, A., Mohammed, H., Ahmed, A. (2021). Assessment of Phenolic and Flavonoid Content of Six Jatropha plants Cultivated in Egypt and Evaluation their Anti-inflammatory and Antioxidant Properties. test, 1(3), 1-8. doi: 10.21608/aijpms.2021.70777.1060
Shimaa Khalifa; Mohamed Sobhy Marzouk; Ahmed Mohamed Metwaly; Hala Mohammed; Amal H. Ahmed. "Assessment of Phenolic and Flavonoid Content of Six Jatropha plants Cultivated in Egypt and Evaluation their Anti-inflammatory and Antioxidant Properties". test, 1, 3, 2021, 1-8. doi: 10.21608/aijpms.2021.70777.1060
Khalifa, S., Marzouk, M., Metwaly, A., Mohammed, H., Ahmed, A. (2021). 'Assessment of Phenolic and Flavonoid Content of Six Jatropha plants Cultivated in Egypt and Evaluation their Anti-inflammatory and Antioxidant Properties', test, 1(3), pp. 1-8. doi: 10.21608/aijpms.2021.70777.1060
Khalifa, S., Marzouk, M., Metwaly, A., Mohammed, H., Ahmed, A. Assessment of Phenolic and Flavonoid Content of Six Jatropha plants Cultivated in Egypt and Evaluation their Anti-inflammatory and Antioxidant Properties. test, 2021; 1(3): 1-8. doi: 10.21608/aijpms.2021.70777.1060

Assessment of Phenolic and Flavonoid Content of Six Jatropha plants Cultivated in Egypt and Evaluation their Anti-inflammatory and Antioxidant Properties

Azhar International Journal of Pharmaceutical and Medical Sciences
Article 1, Volume 1, Issue 3, November 2021, Pages 1-8    PDF (448.46 K)
Document Type: Original research articles
DOI: 10.21608/aijpms.2021.70777.1060
Authors
Shimaa Khalifa* 1; Mohamed Sobhy Marzouk2; Ahmed Mohamed Metwaly3; Hala Mohammed1; Amal H. Ahmed1
1Department of Pharmacognosy, Faculty of Pharmacy,(Girls), Al-Azhar University, Cairo, Egypt
2Department of Chemistry of Tanning Materials and Leather Technology, National Research Center, Giza, Egypt.
3Department of pharmacognosy and Medicinal Plants, Faculty of Pharmacy(Boys), Al-Azhar University, Cairo, Egypt
Abstract
Abstract:
Alcoholic leaves extracts of six species belong to genus Jatrtopha (J. integerrima Jacq, J. integerrima Rosea, J. multifida Linn, J. curcas Linn, J. gossypifolia Linn and J. pandurifolia Andrews) were screened for their total phenolic and flavonoid contents along with evaluation of their in-vitro antioxidant and anti-inflammatory properties. The total phenolic and flavonoid contents were calculated as mg of gallic acid and quercetin equivalents (GAE & QE) / g dry extract by a colorimetric method utilizing Folin-Ciocalteu reagent and AlCl3, respectively. The highest phenolic content was found in J. gossypifolia L. extract (11.21), followed by J. curcas L. (9.14), J. integerrima Jacq (5.01), J. multifida L. (4.26), J. pandurifolia Andr. (3.40) and J. integerrima Rosea (2.16). Moreover, J. gossypifolia L. recorded the highest flavonoid content (7.05), followed by J. curcas L. (6.33), J. integerrima Jacq (3.01), J. pandurifolia Andr. (1.25), J. multifida L (0.98) and J. integerrima Rosea (0.25). Concerning the biological evaluation, DPPH radical scavenging assay and membrane stabilization method were used to determine the antioxidant and anti-inflammatory activities of plant extracts, respectively. The J. gossypifolia L. has shown the best antioxidant activity (94.4%) followed by J. curcas L. (92.5%), J. integerrima Jacq (88.3%), J. multifida L. (73.5%), J. pandurifolia Andr. (66.9%) and J. integerrima Rosea (56.1%).
Keywords
Keywords: Jatropha; Phenolic; flavonoid; Colorimetric; Antioxidant; Anti-Inflammatory
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