Alshemary, A., Sarsık, B., Salman, N., Şahin, S., Şahin, M., Muhammed, Y. (2022). Evaluation of Antibacterial Activity of Calcium Phosphates Based Bone Cements for Biomedical Applications. test, 65(8), 323-335. doi: 10.21608/ejchem.2021.110005.5013
Ammar Z. Alshemary; Betül Sarsık; Nader A. Salman; Sitem Merve Şahin; Mehmet Murat Şahin; Yasser Muhammed. "Evaluation of Antibacterial Activity of Calcium Phosphates Based Bone Cements for Biomedical Applications". test, 65, 8, 2022, 323-335. doi: 10.21608/ejchem.2021.110005.5013
Alshemary, A., Sarsık, B., Salman, N., Şahin, S., Şahin, M., Muhammed, Y. (2022). 'Evaluation of Antibacterial Activity of Calcium Phosphates Based Bone Cements for Biomedical Applications', test, 65(8), pp. 323-335. doi: 10.21608/ejchem.2021.110005.5013
Alshemary, A., Sarsık, B., Salman, N., Şahin, S., Şahin, M., Muhammed, Y. Evaluation of Antibacterial Activity of Calcium Phosphates Based Bone Cements for Biomedical Applications. test, 2022; 65(8): 323-335. doi: 10.21608/ejchem.2021.110005.5013

Evaluation of Antibacterial Activity of Calcium Phosphates Based Bone Cements for Biomedical Applications

Egyptian Journal of Chemistry
Article 30, Volume 65, Issue 8, August 2022, Pages 323-335    PDF (479.82 K)
Document Type: Original Article
DOI: 10.21608/ejchem.2021.110005.5013
Authors
Ammar Z. Alshemary* 1, 2; Betül Sarsık1; Nader A. Salman3; Sitem Merve Şahin4; Mehmet Murat Şahin5; Yasser Muhammed6
1Biomedical Engineering Department, Faculty of Engineering, Karabuk University, Karabuk, 78050, Turkey
2Biomedical Engineering Department, Al-Mustaqbal University College, Hillah, Babil, 51001, Iraq
3Al-Manara College for Medical Sciences, Maysan, 62001, Iraq
4Department of Bioengineering, Hacettepe University, Ankara, 06530, Turkey
5Family Physician, Kurtuluş Family Health Center, Karabük,78200, Turkey
6Aeronautical Techniques Engineering, AL-Farahidi University, Baghdad, Iraq
Abstract
In orthopedics and traumatology surgeries, the repair of bone deformities is a concern. Pure and cobalt (Co) doped calcium phosphate (CaP) cements were successfully prepared in this study. The particles that had been manufactured were characterized utilizing X-ray powder diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), and Scanning electron microscope (SEM) techniques. The lattice properties, degree of crystallinity, and particle size of pure and modified CaP bone cement were reduced dramatically when added cobalt ions. The functional groups of CaP bone cements were detected via the FTIR technique. Antibacterial properties of pure and Co doped CaP bone cement were evaluated qualitatively against Escherichia coli (E. Coli), Methicillin-sensitive Staphylococcus aureus (MSSA). Methicillin-resistant Staphylococcus aureus (MRSA), Methicillin-resistant coagulase-negative staphylococci (MR-CoNS), and Pseudomonas aeruginosa (P. aeruginosa) bacteria for 24 h at 37 ºC. The results showed that the addition of cobalt ions inhibited the growth of E. coli and MSSA bacteria. Antibacterial bone cements are potential material for preventing infection-related bone healing failures.
Keywords
Bone cements; Calcium Phosphate; Cobalt; Antibacterial properties
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