Mohammed Roushdy, M., Ragheb Elsherif, M., Saleh Kayed, E., Farghaly, S., Sayed, A. (2021). Role of diffusion magnetic resonance imaging (DWI) in laryngeal carcinoma. test, 7(3), 19-28. doi: 10.21608/ejnso.2021.212192
Mohammed Mahmoud Mohammed Roushdy; Mahmoud Ragheb Elsherif; Ezzat Mohamed Saleh Kayed; Shimaa Farghaly; Ahmed Ragab Sayed. "Role of diffusion magnetic resonance imaging (DWI) in laryngeal carcinoma". test, 7, 3, 2021, 19-28. doi: 10.21608/ejnso.2021.212192
Mohammed Roushdy, M., Ragheb Elsherif, M., Saleh Kayed, E., Farghaly, S., Sayed, A. (2021). 'Role of diffusion magnetic resonance imaging (DWI) in laryngeal carcinoma', test, 7(3), pp. 19-28. doi: 10.21608/ejnso.2021.212192
Mohammed Roushdy, M., Ragheb Elsherif, M., Saleh Kayed, E., Farghaly, S., Sayed, A. Role of diffusion magnetic resonance imaging (DWI) in laryngeal carcinoma. test, 2021; 7(3): 19-28. doi: 10.21608/ejnso.2021.212192

Role of diffusion magnetic resonance imaging (DWI) in laryngeal carcinoma

Egyptian Journal of Neck Surgery and Otorhinolaryngology
Article 3, Volume 7, Issue 3, December 2021, Pages 19-28    PDF (667.42 K)
Document Type: Original Article
DOI: 10.21608/ejnso.2021.212192
Authors
Mohammed Mahmoud Mohammed Roushdy1; Mahmoud Ragheb Elsherif2; Ezzat Mohamed Saleh Kayed2; Shimaa Farghaly3; Ahmed Ragab Sayed4
1Otorhinolaryngology in Otorhinolaryngology department Assiut university hospital, Assiut University, Assiut, Egypt
2Otorhinolaryngology in Otorhinolaryngology department Assiut university hospital. , Assiut University, Assiut, Egypt
3Radiodiagnosis in Radio-diagnosis department Assiut university hospital, Assiut University, Assiut, Egypt
4Otorhinolaryngology department in Assiut university hospital. , Assiut University, Assiut, Egypt
Abstract
Background and Purpose: To detect sensitivity and specificity of diffusion-weighted imaging (DWI) as a non-invasive technique in the detection of de-novo cases of cancer larynx
Patients and methods: Patients included in this research were patients suspected of de-novo cancer larynx; This study is a prospective randomized comparative clinical trial.
Results: The mean apparent diffusion coefficient (ADC) of laryngeal lesions (0.73± SD 0.23 x10-.3 mm2) was lower (p < 0.001) than the mean of the normal part of the larynx in the same patients (1.09± SD 0.099 x 10-.3 mm2), The cut-off value of the ADC using receiver operating characteristics was Conclusion: DWI is an easily reproducible and non-invasive technique that can accurately explore the larynx and became a very important diagnostic tool of laryngeal diseases. This study demonstrated the cut-off point of ADC value for discrimination of malignant lesion is <0.87x 10-.3 mm2/s with restricted diffusion in DWI images.
Keywords
Diffusion-weighted imaging; laryngeal cancer; new technology in denovo cancer larynx
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