Phytochemical Screening and Antimicrobial activity of Physalis peruviana L. calyces | ||
| Journal of Advanced Pharmacy Research | ||
| Article 1, Volume 6, Issue 1, January 2022, Pages 1-5 PDF (237.33 K) | ||
| Document Type: Research Article | ||
| DOI: 10.21608/aprh.2021.104236.1144 | ||
| Authors | ||
| Eslam Korany1; Hesham Soliman1; Maryam Abd El Gawwad2; Nora El Naggar2; Haitham Ibrahim* 1 | ||
| 1Pharmacognosy Department, Faculty of Pharmacy, Helwan University, Ain Helwan, Cairo, 11795 | ||
| 2Microbiology Department, Faculty of Pharmacy, Helwan University, Ain Helwan, Cairo, 11795 | ||
| Abstract | ||
| Background: The Goldenberry (Physalis peruviana L.) calyces are rich in phytochemical compounds which have promising biological activity. Objective: In the present study, a preliminary phytochemical screening was performed to explore the nature of calyces. The total methanolic extract and n-butanol fraction of P. peruviana calyces were investigated in terms of their antimicrobial activity. Method: Methanol extract and n-butanol fraction were tested for their anti-microbial activity against Gram-positive, Gram-negative bacteria, and Candida albicans using the disc diffusion method. Results: Phytochemical screening showed that calyces are rich in saponins, flavonoids, Steroids and/or triterpenes, Carbohydrates and/or glycosides; while Alkaloids and/or nitrogenous base, tannins, Anthraquinones were absent. The n-butanol fraction showed inhibition zones (16 ± 0.16 mm) for B. subtilis and (10 ± 0.17 mm) for S. aureus, while the methanolic extract showed inhibition zones of (13 ± 0.21 mm) and (8 ± 0.18 mm) for B. subtilis and S. aureus, respectively. On the other hand, no inhibition zones were detected for Gram-negative bacteria or C. albicans Conclusion: The total methanolic extract and n-butanol fraction displayed strong antibacterial activity against B. subtilisthan S. aureus, while both of them didn’t show activity against Gram-negative strains or C. albicans | ||
| Keywords | ||
| Physalis peruviana L; calyces; Antimicrobial; Inhibition zone | ||
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