Correlation between Left Ventricular Diastolic Dysfunction and Dyslipidemia in Symptomless Patients with Newly Diagnosed Diabetes Mellitus-II | ||
| The Medical Journal of Cairo University | ||
| Article 22, Volume 89, December, December 2021, Pages 2411-2419 PDF (497.65 K) | ||
| DOI: 10.21608/mjcu.2021.216075 | ||
| Authors | ||
| HESHAM EL SAYED LASHIN, M.D.; ABULFETOUH EID ALENANY, M.D.; MUSTAFA MOHAMED ELSANDAROSY, M.D. | ||
| The Departments of Internal Medicine*, Faculty of Medicine, Al-Azhar University, Microbiology & Immunology**, Faculty of Medicine, Tanta University and Cardiology*** Department, MOH - Damietta | ||
| Abstract | ||
| Abstract Background: The frequency of heart failure (HF) in cases with Diabetes mellitus (DM) is elevated even in the nonat-tendance of hypertension (HTN) and coronary artery disorder (CAD). Aim of Study: This study aims to investigate the prevalence of left-ventricular (LV) systolic and diastolic dysfunctions (DD) in symptom less cases with newly diagnosed DM-II, and assess the association among LVDD and dyslipidemia in those cases. Subjects and Methods: This was a cross-sectional research involving cases with a new detected (within 1-yr) DM-II; all cases were aging from 30 to 60-yrs, normo-tensive and clin-ically symptomless and visited the out-patient clinics of the endocrinology unit at Mustasharak Hospital from January 2020 to the end of June 2021, Demographic parameters, risk-factors and waist-hip ratio (WHR) were evaluated. Blood specimens for lab analyzing were collected. Comprehensive echo-cardiography has been done to assess systolic and diastolic functions (DF). Results: LA size and volume index, de-acceleration time and E/e’ were highly significant in DM-cases with HbA1c >!7.5 in comparison to diabetics with normal HbA1c. Mean-while, E wave, E/A ratio and Isovolumetric relaxations time were low significantly in DM-cases with HbA1c >!7.5. More-over, there was a highly significance change among the study groups in regard to diastolic function grades. Conclusion: Diastolic dysfunction (DD) has a high prev-alence in a newly detected DM-cases and looks to be associated positively with the HbA1c-levels, dyslipidaemia, obesity, and the DM period. | ||
| Keywords | ||
| Diastolic dysfunction; Left ventricular; DM-II; Dys lip idemia | ||
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