Semeda, A., Yousef, I., Roushdy, A. (2020). Is Lidocaine better than Magnesium Sulfate as an adjuvant with propofol in Colonoscopy?. test, 31(4), 95-100. doi: 10.21608/mjmr.2022.217133
Ahmed M. Semeda; Ibrahim A. Yousef; Al Shimaa I. Roushdy. "Is Lidocaine better than Magnesium Sulfate as an adjuvant with propofol in Colonoscopy?". test, 31, 4, 2020, 95-100. doi: 10.21608/mjmr.2022.217133
Semeda, A., Yousef, I., Roushdy, A. (2020). 'Is Lidocaine better than Magnesium Sulfate as an adjuvant with propofol in Colonoscopy?', test, 31(4), pp. 95-100. doi: 10.21608/mjmr.2022.217133
Semeda, A., Yousef, I., Roushdy, A. Is Lidocaine better than Magnesium Sulfate as an adjuvant with propofol in Colonoscopy?. test, 2020; 31(4): 95-100. doi: 10.21608/mjmr.2022.217133

Is Lidocaine better than Magnesium Sulfate as an adjuvant with propofol in Colonoscopy?

Minia Journal of Medical Research
Volume 31, Issue 4, October 2020, Pages 95-100    PDF (362.29 K)
Document Type: Original Article
DOI: 10.21608/mjmr.2022.217133
Authors
Ahmed M. Semeda1; Ibrahim A. Yousef1; Al Shimaa I. Roushdy2
1Department of Anesthesia, El-Minia Faculty of Medicine
2Department of Anesthesia, El-Minia Faculty of Medicin
Abstract
Background: Colonoscopy is one of the most commonly performed outpatient procedures 
throughout the world as a screening, diagnostic, and therapeutic tool. propofol is the most 
common drug used for sedation during endoscopy either alone or in combination with another 
agent. Patients and Methods: A total of 90 patients of both gender aged between 18 and 70 
years with American Society of Anesthesiologists grade I and II patients scheduled to 
undergo colonoscopy, under sedation were included in the study. Patients were randomly 
allocated into 3 equal groups each containing 30 patient. Group (L) received 1.5 mg/ kg of 
lidocaine IV before induction by propofol and continuous infusion of lidocaine 4 mg kg/ h 
after induction, group (M) received50 mg/ kg of magnesium sulphate before induction by 
propofol and continuous infusion of magnesium 8 mg/ kg/h after induction and group (O) as 
control group received normal saline 0.9% Sodium Chloride. Results: There was a significant 
difference in intraoperative hemodynamic stability, total amount of propofol, post procedural 
pain and analgesic demand, and patient between three groups. Conclusion: we concluded that 
lidocaine infusion by dose 1.5 mg/kg loading and 4 mg/kg/ h as maintenance is more effective 
than magnesium sulfate by dose 50 mg/kg loading and 8 mg/kg/ h maintenance in decreasing 
total amount of propofol, post procedural pain and analgesic demand, and improving patient 
satisfaction in patient undergoing colonoscopy under sedation with propofol.
Keywords
PSA; colonoscopy; lidocaine; magnesium
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