Haroun, H., Saeed, M., Thabet Labeb, B. (2022). Comparison in Macular Thickness between Non diabetic and Uncomplicated Diabetics after Uncomplicated Phacoemulsification. test, 3(1), 95-105. doi: 10.21608/ejmr.2022.218103
Hazem Effat Haroun; Mostafa Abdel Naby Saeed; Bakhoum Henri Thabet Labeb. "Comparison in Macular Thickness between Non diabetic and Uncomplicated Diabetics after Uncomplicated Phacoemulsification". test, 3, 1, 2022, 95-105. doi: 10.21608/ejmr.2022.218103
Haroun, H., Saeed, M., Thabet Labeb, B. (2022). 'Comparison in Macular Thickness between Non diabetic and Uncomplicated Diabetics after Uncomplicated Phacoemulsification', test, 3(1), pp. 95-105. doi: 10.21608/ejmr.2022.218103
Haroun, H., Saeed, M., Thabet Labeb, B. Comparison in Macular Thickness between Non diabetic and Uncomplicated Diabetics after Uncomplicated Phacoemulsification. test, 2022; 3(1): 95-105. doi: 10.21608/ejmr.2022.218103

Comparison in Macular Thickness between Non diabetic and Uncomplicated Diabetics after Uncomplicated Phacoemulsification

Egyptian Journal of Medical Research
Article 8, Volume 3, Issue 1, January 2022, Pages 95-105    PDF (336.33 K)
Document Type: Original Article
DOI: 10.21608/ejmr.2022.218103
Authors
Hazem Effat Haroun; Mostafa Abdel Naby Saeed; Bakhoum Henri Thabet Labeb
Department of Ophthalmology, Faculty of Medicine Beni-Suef University
Abstract
Background: Phacoemulsification (phaco) is one of the most widely used cataract surgery techniques nowadays. Various factors can influence the tissue structures of the eyeball eg. Ultrasonic energy, fluidics, mechanical effects, compression, and hypoxia on the tissue. Every step of this maneuver can cause direct or indirect effects on ocular tissues. Ultrasonic energy and fluidics produce mechanical effects that cause an inflammatory reaction which affects cornea, retina and choroid. Objective: To evaluate the effect of phacoemulsification on retina to compare these effects in diabetic and non-diabetic patient to reach a conclusion whether diabetic patient are more vulnerable to these effects or not. Patients and Methods: This is a prospective cohort observational study that included 100 eyes of 100 patients (50 diabetic patients (Type II), 50 non diabetic patients) having immature senile cataract. Patients were recruited from the ophthalmology department of Beni-Suef University. Results: In our study results  noted a statistically significant increase in the central macular thickness 1day, 1 week & 1 month postoperatively also there was no statistically significant difference in the central macular thickness between the Diabetic and Non-diabetic group neither pre-operatively, nor post-operatively. Conclusion: Phacoemulsification affects the macula, phaco power used during the surgery and inflammatory mediators released after the surgery leads to long term increase in Central macular thickness in both diabetic and non-diabetic patients. It was noticed that phacoemulsification causes increase in Central macular thickness noticed at one week & one month post-operatively in both diabetic and non-diabetic patients.  Finally we can say that cataract phacoemulsification cause t increase in central macular thickness.
Keywords
Spectral Domain optical coherence tomography
References
  1. Harrison TR. Diabetes Mellitus. In: Branwald E, Fauci S, Kasper D, Hauser LS, L Longo D, Jameson JL. Harrison Principle of Internal Medicine. 15. USA, Mc Grow-Hill; 2001. p. 2121.
  2. Wild S, Roglic G, Green A, Sicree R, King H. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 2004;27(5): 1.
  3. Lam DW and LeRoith D. The worldwide diabetes epidemic. Current Opinion in Endocrinology, Diabetes and Obesity 2012; 19:93–96.
  4. Holman N, Forouhi NG, Goyder E, Wild SH. The Association of public health bservatories (APHO) Diabetes prevalence model. Diabet Med. 2011; 28(5):575-82047–53.
  5. Facts About Diabetic Eye Disease: The National Eye Institute (NEI) 2015.
  6. Riordan-Eva P, Whitcher J, Vaughan-Whitehead D, Asbury T. Vaughan & Asbury's general ophthalmology. 19th edition; McGraw-Hill Medical: Univerza v Ljubljani, Medicinska fakulteta; 2011.
  7. Klein BEK, Klein R, Moss SE. Prevalence of cataracts in a population-based study of persons with diabetes mellitus. Ophthalmology. 2005;92(9):1191–1196.
  8. Haddad NM, Sun JK, Abujaber S, Schlossman DK, Silva PS. Cataract surgery and its complications in diabetic patients. 2014; 29(5-6):329-37.
  9. Allen HF. Phacoemulsification and Aspiration: The Kelman Technique of Cataract Removal. Arch Ophthalmol. 1976;94(6):1053.
  10. Petrash JM. Aging and age-related diseases of the ocular lens and vitreous body. Invest Ophthalmol Vis Sci. 2013;54: 54–59.
  11. Jaffe GJ, Burton TC, Kuhn E, Prescott A, Hartz A. Progression of non-proliferative diabetic retinopathy and visual outcome after extracapsular cataract extraction and intraocular lens implantation. Am J Ophthalmol. 1992; 114J (4):448–456.
  12. Kim SJ, Flach AJ, Jampol LM. Nonsteroidal anti-inflammatory drugs in ophthalmology. Surv Ophthalmol. 2010; 55(2):108–133
  13. Xu H, Chen M, Forrester JV, Lois N. Cataract surgery induces retinal pro-inflammatory gene expression and protein secretion. Invest Ophthalmol Vis Sci. 2011; 52(1):249–255.
  14. Tso MO, Shih CY. Experimental macular edema after lens extraction. Invest Ophthalmol Vis Sci. 1977;16(5):381–392.
  15. Liu H, Demetriades AM, Xiao WH, Campochiaro PA, Vinores SA. Mouse model of post-surgical breakdown of the blood-retinal barrier. Curr Eye Res. 2004;28(6):421–426.
  16. Manuel SF, Nuno MG, Paulo FC, João BB, Amândio RS, Ângela C, Elisete MB and Fernando MFR. Choroidal and macular thickness changes induced by cataract surgery. Clin Ophthalmol. 2014; 8: 55–60.
  17. Cagini C, Fiore T, Iaccher B, Piccinelli F, Antonietta MR and Fruttini D. Macular Thickness Measured by Optical Coherence Tomography in a Healthy Population Before and After Uncomplicated Cataract Phacoemulsification Surgery, Current Eye Research, 2009; 34(12): 1036–1041.
  18. Giansanti F, Bitossi A, Giacomelli G, Virgili G, Pieretti G, Giuntoli M, Abbruzzese G, Menchini U. Evaluation of macular thickness after uncomplicated cataract surgery using optical coherence tomography. Eur J Ophthalmol. 2013; 23(5):751-6.
  19. von Jagow B, Ohrloff C and Kohnen T. Macular Thickness Measured by Optical Coherence Tomography in a Healthy Population before and After Uncomplicated Cataract Phacoemulsification Surgery. Current Eye Research, 2009; 34(12): 1036–1041.
  20. Miyake K. Prostaglandins as a causative factor of the cystoid macular edema after lens extraction. Nippon Ganka Gakkai Zasshi. 1977; 81(9):1449-1464.
  21. Flach AJ. The incidence, pathogenesis and treatment of cystoid macular edema following cataract surgery. Trans Am Ophthalmol Soc., 1998; 96: 557-34.
 

 

Statistics
Article View: 265
PDF Download: 197