Helicobacter Pylori Infection in Patients with Non Alcholic Fatty Liver Disease | ||
| Benha Medical Journal | ||
| Article 9, Volume 39, Issue 1, March and April 2022, Pages 123-135 PDF (574.08 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/bmfj.2021.73869.1412 | ||
| Authors | ||
| shimaa zordok* 1; yehia sadek2; badawy abdel aziz3; eman behiry4 | ||
| 1Hepatology, Gastroenterology and Infectious Diseases. Faculty of Medicine Benha University | ||
| 2(Professor of Hepatology, Gastroenterology and Infectious Diseases) | ||
| 3Assistant Professor of Hepatology, Gastroenterology and Infectious Diseases | ||
| 4Assistant Professor of Clinical and Chemical Pathology) | ||
| Abstract | ||
| Background: Although there have been conflicting results, several subsequent clinical trials have demonstrated a higher rate of fatty liver and NASH in H. pylori -positive patients compared to HP-negative patients; in addition, small trials examining the effect of H. pylori eradication have shown improvement in markers of NAFLD activity, further supporting a link between these two conditions. Aim: This study was conducted to evaluate the relation of H. Pylori infection with Non Alcholic Fatty Liver Disease (NAFLD). Methods: This study is a case control study carried out at outpatient's clinics of El Mahalla El Aam Hospital from November 2017 till May 2018, Subjects were classified into two groups: One hundred patients with NAFLD who attended outpatient’s clinics of El Mahalla El Aam Hospital, Group (A) (case group): Included 50 patients with NAFLD (diagnosed by ultrasonography). Group (B) (control group): Included 50 subjects (diagnosed by ultrasonography) who will serve as a control group. Results: There was a statistical significant difference in Hp results between group I and group II groups, with significant Ag positive-Ab positive to Group I, and there was no statistical significant differences in US grades of NAFLD according to HP Ag or Ab results. Conclusion: Our study was display a significant increase in MPV in patients with NAFLD. The burden of H. Pylori infection among NAFLD patients was noticeably high, in comparison with the healthy control group. | ||
| Keywords | ||
| Non Alcoholic Fatty Liver Disease; H. pylori; infection; case control | ||
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