Association of Helicobacter pylori Infection and Severity of Coronary Artery Atherosclerosis in Patients with Suspected Coronary Artery Disease | ||
| The Egyptian Journal of Hospital Medicine | ||
| Article 156, Volume 86, Issue 1, January 2022, Pages 963-967 PDF (557.22 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejhm.2022.219973 | ||
| Authors | ||
| Hamdy Abdel Azeem; Mohamed S. Zaghlol; Mohamed M. Elawady; Majid Darraj | ||
| Abstract | ||
| Background: There is a strong correlation between Helicobacter pylori (HP) infection and coronary artery disease (CAD). There is also a strong correlation between HP infection and the severity of coronary artery atherosclerosis in patients with CAD. Our study determined the association of HP infection and severity of coronary artery atherosclerosis in patients with suspected CAD. Methods: A prospective study of 100 individuals who had coronary angiography for coronary atherosclerosis was conducted. Body mass index (BMI), blood pressure, blood cholesterol, blood glucose, leukocyte count, hemoglobin, and urea breath test were all done on the patients. Coronary angiograms were graded based on vascular and angiographic severity scores. Results: Triglyceride, (TG), Low Density Lipoprotein (LDL), C- Reactive Protein (CRP), Erythrocyte Sedimentation Rate (ESR), vessel score, and angiographic severity score all showed high correlations with Gensini score. There was a substantial association between vessel score and TG, LDL and angiographic severity score. It was found that angiographic severity score has a substantial positive link to a person's BMI; LDL; CRP; ESR, and vessel score. Conclusion: Although HP infection has been linked to an increased risk of coronary artery disease (CAD), established risk variables outweigh their potential impact. | ||
| Keywords | ||
| Atherosclerosis; Coronary artery disease; Helicobacter pylori; Inflammation | ||
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