Role of helicobacter pylori in cases of benign laryngeal lesions | ||
| Minia Journal of Medical Research | ||
| Volume 31, Issue 2, April 2020, Pages 1-7 PDF (155.14 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/mjmr.2022.220823 | ||
| Authors | ||
| Mohammed A. Gomaa1; Rehab K. Mohammed2; Amal R. Ahmed Ali1; Khalaf H. Mohammed1 | ||
| 1Department of Otorhinolaryngology, faculty of medicine, El-Minia University, Egypt | ||
| 2Department of Pathology, faculty of medicine, El-Minia University, Egypt . | ||
| Abstract | ||
| Introduction: Larynx can be involved with malignant or a spectrum of benign lesions. Benign lesions of the larynx involve mainly chronic laryngitis, vocal cord polyp, vocal cord nodule, Reinke’s edema and various different benign lesions. Smoking and voice abuse seem to be the most common cause and risk factor of laryngeal disorders. Helicobacter pylori (HP) were detected in some cases of chronic laryngitis. However, it has been confirmed by histology, tissue cultures or polymerase chain reaction in benign laryngeal lesions. Patient and methods: 40 patients of both sex, aged 6-75 years old, scheduled to undergo surgical excision of benign laryngeal lesions and histopathological examination to diagnose HP were enrolled in this prospective study. Follow up of laryngopharyngeal reflux (LPR), HP stool antigen test and histopathological evaluation of the biopsies to diagnose HP in the lesions. Results: When we compared between positive cases which was 8 by Giemsa stain and negative cases (32 cases), there was no statistically significant difference according to age, sex and LPR. But there was statistically significant difference regarding the different types of laryngeal lesions with the majority of positive cases found in patients with vocal fold polyp. There was also statistically significant difference as regard stool antigen test which showed significant agreement. Conclusion: HP may be considered as a reliable cause and risk factor for benign laryngeal lesions especially VF polyp. Also stool antigen test could be used as a reliable test for diagnosis of HP such as histopathological examination. | ||
| Keywords | ||
| Helicobacter pylori (HP); Laryngopharyngeal reflux (LPR); Vocal fold (VF) and Benign laryngeal lesions. | ||
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