Comparison between central venous and arterial gases level versus lactate clearance as an indicator of initial resuscitation in septic patients in intensive care unit | ||
| Minia Journal of Medical Research | ||
| Volume 31, Issue 2, April 2020, Pages 335-339 PDF (362.05 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/mjmr.2022.221095 | ||
| Authors | ||
| Ibrahim A. Youseif; Ahmad H. Mohammed; Rehab M. Farghly | ||
| Department of Anesthesia,intensive care and pain management; Minia Faculty of Medicine; Egypt | ||
| Abstract | ||
| Objective: Aim of this study: was to compare the central venoarterial carbon dioxide difference/arterial-central venous oxygen difference (P(va)CO2/C(a-v)O2) ratio versus lactate clearance as an indicator to evaluate the steps of initial resuscitation in septic patients. Patients and methods: Our study was conducted in the ICU,Minia University Hospital. Eighty patients with severe sepsis or septic shock. Results: There was improvement in CVP, MAP, or Scvo2 at T8 after early resuscitation with no significant differences between group1 and group 2 and inside each group. There were no significant difference in P(v-a)CO2/C(av)O2 ratio at T0 and at T8 at group 1. However there was higher lactate level at T0 and exhibited significantly lower at T8 in group 2. Conclusion: Further clinical trials are needed to conclusively establish lactate clearance as a resuscitation endpoint and an outcome measure to be targeted during the most proximal phases of severe sepsis and septic shock. | ||
| Keywords | ||
| CVP; MAP; Scvo2 | ||
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