El sayed, M., Halawa, A., kandil, M., Shenoda, A. (2022). Effectiveness of Different Types of Intraarticular Injections for the Knee Osteoarthritis; a Systemic Review. test, 39(1), 191-203. doi: 10.21608/bmfj.2021.90036.1455
Magdy El sayed; Abdelsamie Halawa; Mahmoud kandil; Androw Shenoda. "Effectiveness of Different Types of Intraarticular Injections for the Knee Osteoarthritis; a Systemic Review". test, 39, 1, 2022, 191-203. doi: 10.21608/bmfj.2021.90036.1455
El sayed, M., Halawa, A., kandil, M., Shenoda, A. (2022). 'Effectiveness of Different Types of Intraarticular Injections for the Knee Osteoarthritis; a Systemic Review', test, 39(1), pp. 191-203. doi: 10.21608/bmfj.2021.90036.1455
El sayed, M., Halawa, A., kandil, M., Shenoda, A. Effectiveness of Different Types of Intraarticular Injections for the Knee Osteoarthritis; a Systemic Review. test, 2022; 39(1): 191-203. doi: 10.21608/bmfj.2021.90036.1455

Effectiveness of Different Types of Intraarticular Injections for the Knee Osteoarthritis; a Systemic Review

Benha Medical Journal
Article 14, Volume 39, Issue 1, March and April 2022, Pages 191-203    PDF (656.34 K)
Document Type: Review Article
DOI: 10.21608/bmfj.2021.90036.1455
Authors
Magdy El sayed1; Abdelsamie Halawa1; Mahmoud kandil1; Androw Shenoda* 2
1orthopedic surgery Faculty of medicine – Benha University
2MBBCH
Abstract
Background: Osteoarthritis (OA) is most prevalent type of arthritis, which significantly affects the patient’s mobility complex. The aim to evaluate the evidence from the literature regarding the superiority of platelet-rich plasma (PRP), hyaluronic acid (HA), or corticosteroids (CS) over each other's. Methods: An electronic search was coducted between January 2010 to March 2021 in different databases; PubMed, SCOPUS, Web of Science, and Cochrane Central Register of Controlled Trials (CENTRAL). Included randomized, nonrandomized trials that were published in English with full text available. Results: From a total 6912 screened citations, thirty studies met our inclusion criteria with a total 3303 cases. Most on included studies (N=13) compared platelet-rich plasma to hyaluronic acid and six studies compared hyaluronic acid to cortico-steroids, four studies compared hyaluronic acid to hyaluronic acid + cortico-steroids , one study compared platelet-rich plasma to cortico-steroids and another study compared platelet-rich plasma to hyaluronic acid acid , cortico-steroids. Regarding platelet-rich plasma compared to hyaluronic acid, evidence favored platelet-rich plasma over hyaluronic acid in majority of studies, the effect of platelet-rich plasma lasted longer up to 12 months, and it might be extended to 18 months if intra-osseous injection would be considered. On the other hand, hyaluronic acid should moderate efficacy over cortico-steroids injection but its effects survived only up to six months. Conclusion; platelet-rich plasma is most effective type on the long term and it provides pain relief up to 12 months especially in cases with low grades osteoarthritis and young age patients.
Keywords
Intraarticular; Injections; Knee; Osteoarthritis
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