Correlation between Allopurinol and Epinephrine in the prevention of post Endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis | ||
| Minia Journal of Medical Research | ||
| Article 7, Volume 30, Issue 4, October 2019, Pages 29-38 PDF (199.33 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/mjmr.2022.221613 | ||
| Authors | ||
| Mohamed A. Abdelaleem Elsherbiny1; Madeha M. Ahmed Makhlof1; Ayman M. Hassanin Hassan2; Hala I. Mohamed Ahmed1; Magdy F. Ahmed Mahmoud1 | ||
| 1Department of Tropical Medicine; Minia University; Faculty of medicine-Egypt | ||
| 2Department of General Surgery; Minia University; Faculty of medicine-Egypt | ||
| Abstract | ||
| This study was done to evaluate and investigate the effects of using different drugs on reducing the frequency and severity of Post- ERCP pancreatitis. The study was done on 90 randomized patients with extrahepatic cholestasis and divided into three groups. Post ERCP pancreatitis was diagnosed by laboratory investigations, ultra-sonography and triphasic abdominal CT criteria of pancreatitis. The results of this study showed that there was a statistically significant difference in the percentage of knife precut between the studied groups. There was a statistically significant difference in the degree of post ERCP pancreatitis during comparison the control group with each studied drug group, in which allopurinol has a protective role in the occurrence of post ERCP pancreatitis by regression analysis. It is concluded to use allopurinol before ERCP procedure. | ||
| Keywords | ||
| ERCP; pancreatitis; knife precut; Allopurinol | ||
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