Sarcopenia in Chronic Liver Diseases | ||
| Minia Journal of Medical Research | ||
| Article 19, Volume 30, Issue 3, July 2019, Pages 100-104 PDF (416.84 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/mjmr.2022.221879 | ||
| Authors | ||
| Mahmoud A. Khattab1; Nadia F. El-Amin2; Mohamed O. Abdel-Aziz1; Victoria M. Saleeb3 | ||
| 1Department of Internal Medicine, Faculty of Medicine, Minia University, P O:61111 | ||
| 2Department of Radiology, faculty of Medicine, Minia University, PO: 61111 | ||
| 3Department of Internal Medicine, Faculty of Medicine, Minia University, P O:61111. | ||
| Abstract | ||
| Background: Sarcopenia is defined as a muscle mass two standard deviations below the healthy young adult mean, and although it is associated with aging, it can also be present as a result of chronic diseases and malignancy, and it ultimately leads to decreased functional capacity and higher risk of morbidity and mortality in different groups of patients. Aim of The work: The aim of this study is to investigate the frequency of sarcopenia in HCV induced chronic liver diseases. Subjects and Methods: This case control hospital based study recruited patients with HCV-induced chronic liver disease of different functional grades according to Child-Pough and Meld scores and a group of healthy subjects as controls. All participants were assessed for demographic, hematological, and biochemical liver and renal profiles. Radiological diagnostic parameters of sarcopenia were determined by subjecting all participants to MDCT abdominal scan at the level of psoas muscle. Results: Using computed tomography measurement of psoas muscle thickness/height as a diagnostic validated test for sarcopenia, sarcopenia was detected in 52.5% of our liver cirrhosis patients. Conclusion and future recommendations In conclusion, sarcopenia is a common complication of cirrhosis and adversely affects survival, quality of life, and response to stress including infection and surgery. | ||
| Keywords | ||
| Sarcopenia; HCV; Cirrhosis. | ||
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