Gaafar, H., Kheir, G., El Dawody, A., El Arman, M., Senna, M. (2022). Assessment of Carotid Atherosclerosis in Patients with Knee Osteoarthritis. test, 10(10), 54-72. doi: 10.21608/muj.2022.112194.1082
Heba Elsayed Gaafar; Germen Albair Kheir; Abeer Abd El Hamid El Dawody; Mohamed Mohamed El Arman; Mohamed Kamal Senna. "Assessment of Carotid Atherosclerosis in Patients with Knee Osteoarthritis". test, 10, 10, 2022, 54-72. doi: 10.21608/muj.2022.112194.1082
Gaafar, H., Kheir, G., El Dawody, A., El Arman, M., Senna, M. (2022). 'Assessment of Carotid Atherosclerosis in Patients with Knee Osteoarthritis', test, 10(10), pp. 54-72. doi: 10.21608/muj.2022.112194.1082
Gaafar, H., Kheir, G., El Dawody, A., El Arman, M., Senna, M. Assessment of Carotid Atherosclerosis in Patients with Knee Osteoarthritis. test, 2022; 10(10): 54-72. doi: 10.21608/muj.2022.112194.1082

Assessment of Carotid Atherosclerosis in Patients with Knee Osteoarthritis

Medicine Updates
Article 6, Volume 10, Issue 10, July 2022, Pages 54-72    PDF (1.15 M)
Document Type: Original Article
DOI: 10.21608/muj.2022.112194.1082
Authors
Heba Elsayed Gaafar* 1; Germen Albair Kheir2; Abeer Abd El Hamid El Dawody3; Mohamed Mohamed El Arman4; Mohamed Kamal Senna5
1Rheumatology department, Port said faculty of medicine, Port Said, Egypt
2Radiology Department, Mansoura faculty of medicine, Mansoura, Egypt
3Rheumatology Department, Mansoura faculty of medicine, Mansoura, Egypt
4Clinical Pathology department, Mansoura faculty of medicine, Mansoura, Egypt
5Rheumatology department, Mansoura faculty of medicine, Mansoura, Egypt
Abstract
A total of 100 consecutive patients with primary symptomatic KOA were invited to participate in this study. Patients were recruited from the Outpatient Rheumatology Clinic at Mansoura University Hospitals. The study included also 100 consecutive non-KOA subjects matched for age, sex and BMI with KOA patients. All patients met the 2010 EULAR criteria for diagnosis of KOA and patients had to show evidence of radiological changes of KOA by plain radiography and Knee Ultrasonography. Blood samples were collected from all participants to test for ESR, CRP, fasting blood sugar and lipid profile. Assessment of carotid atherosclerosis is made by measurements of Carotid intima media thickness (cIMT). Comparison between KOA group and non-KOA group was done and revealed that cIMT differed significantly among the KOA subgroups based on KL grading being thickest in the KOA-KL4 subgroup of patients.The rate of presence of carotid plaques differed among the groups, with rate being highest in KOA-KL4 subgroup (79.2%), followed by KOA-KL3 subgroup (35.7%) and is lowest in KOA-KL2 subgroup (8.3%). These differences were significant (p < 0.001).
Keywords
Knee osteoarthritis; Carotid atherosclerosis; Carotid plaques; Carotid intima media thickness; Metabolic syndrome
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