Immunohistochemical study of GATA3 and Androgen receptors in breast cancer | ||
| Minia Journal of Medical Research | ||
| Volume 30, Issue 1, March 2019, Pages 233-235 PDF (151.2 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/mjmr.2022.223019 | ||
| Authors | ||
| Manal I. Abd Elghany; Fatma El Zahraa A. Saleh; Nisreen D. Mohamed; Maggie S. Boshra | ||
| Department of Pathology, El-Minia Faculty of Medicine | ||
| Abstract | ||
| Introduction: Breast carcinoma (BC) is a major global problem, with nearly 1.7 million new cases occurring among women worldwide each year (International Agency for Research on Cancer. 2016). The aim of this work was to: Study the immunohistochemical expressions of GATA 3 binding protein (GATA3) and Androgen receptor (AR) in invasive duct carcinoma. Material and Methods: Tissue specimens: The present study comprised 61 formalin – fixed, parafin – embedded tissue specimen invasive duct breast carcinoma. They were randomly selected and retreived from the archives of histopathological laboratories of Minia oncology center, pathology department, in period between 2012 and 2016. Results: Clinicopathological features: The current study included 61 cases of invasive duct carcinoma (NST) of female breast. Data regarding different clinical and histopathological features for cases investigated in this study. Discussion: Breast cancer (BC) is one of the most frequent cancers worldwide and is considered the second leading cause of carcinoma related death (15%) after lung carcinoma (Baade, 2017). Summary: Breast carcinoma (BC) is a major global problem, with nearly 1.7 million new cases occurring among women worldwide each year. | ||
| Keywords | ||
| Breast carcinoma (BC); Expressions of GATA 3 | ||
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