Growth and Developmental Milestones in children with Congenital Hypothyroidism Attending Assiut Health Insurance Clinic. | ||
| The Egyptian Journal of Community Medicine | ||
| Article 2, Volume 40, Issue 4, October 2022, Pages 233-242 PDF (497.37 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejcm.2022.113872.1199 | ||
| Authors | ||
| Marian Maged Habib* 1; Hala Hassan I Abou faddan2; Kotb Abbass Metwalley3; Taghreed Abdul-Aziz Mohammad Ismail4 | ||
| 1Assiut genetic counselling centre, General Administration for Disability Reduction, MOHP, Assiut Governorate, Egypt. | ||
| 2Public health and community medicine, faculty of medicine, Assiut University | ||
| 3Pediatric endocrinology unit.Pediatric department, Faculty of medicine, Assiut University, Assiut, Egypt | ||
| 4Public Health and Community Medicine Department, Faculty of Medicine, Assiut University | ||
| Abstract | ||
| Objective: Determine the effect of CH on growth and development of children aged 1–60 months compared to normal children. Methodology: A cross sectional study with comparison group comprising 118 children with CH and 236 normal children was conducted in Assiut, Egypt. Growth was measured by weight and length/height. Developmental delay was screened using the ASQ3. Results: Mean age in both groups was 19.6 months. Mean weight of CH cases was 6991.3±1907.4 gm versus 6912.3±188.2 gm for normal children in children aged 1- Regarding thyroid function, 15% and 23% of CH cases revealed overt and subclinical hypothyroidism respectively. Overt hypothyroidism showed significantly higher developmental delays than either eu-thyroid or subclinical cases in the communication gross motor, fine motor, and personal–social domains (64.7%, 42.9%, 43.8% and 42,9% respectively) Conclusion: CH children were significantly overweight, stunted and developmentally delayed compared to normal children. Impaired thyroid function was not associated with growth defects but overt hypothyroid cases showed significant developmental delay. IQ testing and continuous monitoring are essential for all children with CH. Efficiently organized recording systems, treatment documents, and compliance and follow-up assessment results can facilitate hassle-free health-card retrieval . | ||
| Keywords | ||
| congenital hypothyroidism; developmental milestones; Egypt; growth; neonatal screening | ||
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