Assessment of Heart Rate Variability in Young Patients with Primary Hypertension | ||
| The Egyptian Journal of Hospital Medicine | ||
| Article 2, Volume 74, Issue 2, January 2019, Pages 226-236 PDF (590.01 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejhm.2019.22839 | ||
| Authors | ||
| Mansour M. Moustafa; Mohamed Samy; Mohamed Omar* | ||
| Cardiology Department, Faculty of Medicine, Al-Azhar University (Cairo) | ||
| Abstract | ||
| Objective: this study aimed to determine the association between HRV and hypertension young adult patients, the effect of antihypertensive medications on HRV parameters was also studied. Subjects and Methods: 70 subjects under age of 40 years were classified into two groups: A- Patients’ group, It included 50 subjected they were classified according to type of antihypertensive medications into 3 subgroups; 1): 20 patients on ACE-I, (2): 15 patients on BB, 3): 15 patients on CCB. B)- Control group included 20 healthy subjects. Pulse rate, BP, ECG, and 24h Holter monitor were used to measure heart rate variability (HRV). Results: high statistical significant difference was found between patients and control according to SDNN rMSSD, pNN50 and LF/HF ratio ( P < 0.001). HRV parameters showed improvement in patient treated by BB and ACE-I, whereas no improvement was seen in patients treated by CCB. Conclusion: disturbed cardiac autonomic function was found in young hypertensive patients, treating such patients with either BB or ACE-I was associated with improvement of such autonomic imbalance. | ||
| Keywords | ||
| Primary hypertension; Autonomic nervous system; ambulatory blood pressure; Dipping; Heart Rate Variability | ||
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