Biosynthesized Silver Nanoparticles Induced Potential Antibacterial Activity | ||
| Egyptian Journal of Medical Microbiology | ||
| Article 9, Volume 31, Issue 2, April 2022, Pages 49-55 PDF (625.16 K) | ||
| Document Type: New and original researches in the field of Microbiology. | ||
| DOI: 10.21608/ejmm.2022.228625 | ||
| Authors | ||
| Khalid Abdalla Ali AbdelRehim* 1; Ahmed Mohamed Ali Mohamed2; Sulaiman A Al Yousef3; Alyousef Ali4 | ||
| 1Botany dept., Faculty of science, Sohag university - Sohag - Egypt | ||
| 2Department of Biology, Preparatory Year, Shaqra University, Saudi Arabia. | ||
| 3Department of Clinical Laboratory Sciences, College Of Applied Medical Science, University of Hafr Albatin, P. O. Box 1803, Hafar Al Batin 31991, Saudi Arabia | ||
| 4MOH, Saudia Arabia | ||
| Abstract | ||
| Background: Nanoparticles especially those synthesized biologically are promising in its applications in medical field. The nanoparticles synergic effect with common used antibiotics are the most targeted studies nowadays, in order to overcome the microbial antibiotic resistance problem. Objectives: To synthesize silver-nanoparticles (AgNPs) using desert plant Alhagi maurorum (am), and to examine their effects in improvement the antibiotics efficiency. Methodology: Extracellular silver-nanoparticles biosynthesis using Alhagi maurorum (desert plant). The synthesized silver-nanoparticles were characterized using UV-visible spectroscopy, scanning electron microscopy-energy dispersive spectroscopy (SEM-EDS), X–ray diffraction (XRD) and zeta potential in order to investigate their structural, and textural properties.Synergistic effect ofAgNPs plus antibiotics was also measured. Results: The UV-visible absorbance showed a strong intense peaks at 375 nm The XRD showed diffraction peaks at 2θ=32.12°, 44.76°, 46.22° corresponding to the (122), (200), (231) which agreed with the quality value (JCPDS card No. 04-0783). SEM–EDS and XRD analysis confirmed the crystalline nature of silver-nanoparticles with spherical, oval and hexagonal in shape ranged from 37-79 nm in size. DLS analysis showed the size distribution of silver-nanoparticles with maximum intensity at 70 nm. The silver-nanoparticles showed considerable synergistic effect with different antibiotics. Conclusion: Silver can be reduced to nanoparticles by Alhagi maurorum extract. Considerable synergic effects were recorded by applying nanoparticles with diversified antibiotics on different pathogenic bacteria. | ||
| Keywords | ||
| Biosynthesis; Silver Nanoparticles; Antibiotics; Synergistic; Alhagi maurorum | ||
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