Protective and therapeutic effect of myrrh herb (Commiphora molmol) on inhibited immune system in experimental rats | ||
| African Journal of Biological Sciences | ||
| Article 1, Volume 18, Issue 1, June 2022, Pages 1-14 PDF (1.05 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ajbs.2022.230599 | ||
| Authors | ||
| Soha M Ibrahim1; Ekbal M Mohamed* 2; El-Sayeda G. E. El-Sahar2; Hala R Ataya2 | ||
| 1Food Industries Department, Faculty of Agriculture, Ain Shams University | ||
| 2Home Economics Department, Faculty of Specific Education, Ain, Shams University | ||
| Abstract | ||
| The present work aimed to study the therapeutic and protective effect of feeding myrrh against immunity inhibition causative to male rats. Forty eight rats were used in this study. They were divided into 8 groups, each one of 6 rats, the first group was the (-ve) control, the second group was left as a (+ve) control group. Groups (3, 4 & 5) were induced immunity inhibition for them at the end of experiment and received myrrh with (50, 100 & 150) mg/kg, respectively for four weeks. Groups (6, 7 & 8) were induced immunity inhibition for them at the beginning of the experiment and received myrrh with (50, 100 & 150) mg/kg, respectively for four weeks. Results revealed that rats in the protective groups (3, 4 and 5), or therapeutic groups (6, 7 and 8) showed significant increased values in levels of their immunity protein (IgG) when compared with untreated rats (+ve group 2). Lymphocytes, total protein and albumin also increased significantly compared to untreated rats (+ve group 2), while their globulin, creatinine, total bilirubin, GPT, GOT and erythrocytes were significantly decreasing compared to control negative group. Group 5 (protective) that had myrrh (150mg/kg) showed highly increase in its immune efficiency. The histopathological examinations of thymus gland and spleen showed relatively no alteration in their structure in rats that were received myrrh at the beginning of the experiment before induced immunity inhibition to them. In conclusion myrrh can be used to increase the protective and therapeutic effect for immunity disorders, and to protect the body and raise its immune efficiency n rats. | ||
| Keywords | ||
| Immune system - Myrrh-IgG- histopathological structure; thymus gland; spleen; rats | ||
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