Elgazzar, M., AlRakhawy, H., Metawaa, N., Wahdan, A., Alshafiey, M. (2022). Efficacy of intra Pleural streptokinase injection in Post traumatic Clotted Hemothorax. test, 39(2), 409-417. doi: 10.21608/bmfj.2022.37822.1299
Mohammed Ahmed Elgazzar; Hany Mohammed AlRakhawy; Noha Metawaa; Ashraf Mostafa Wahdan; Mahmoud Ahmed Alshafiey. "Efficacy of intra Pleural streptokinase injection in Post traumatic Clotted Hemothorax". test, 39, 2, 2022, 409-417. doi: 10.21608/bmfj.2022.37822.1299
Elgazzar, M., AlRakhawy, H., Metawaa, N., Wahdan, A., Alshafiey, M. (2022). 'Efficacy of intra Pleural streptokinase injection in Post traumatic Clotted Hemothorax', test, 39(2), pp. 409-417. doi: 10.21608/bmfj.2022.37822.1299
Elgazzar, M., AlRakhawy, H., Metawaa, N., Wahdan, A., Alshafiey, M. Efficacy of intra Pleural streptokinase injection in Post traumatic Clotted Hemothorax. test, 2022; 39(2): 409-417. doi: 10.21608/bmfj.2022.37822.1299

Efficacy of intra Pleural streptokinase injection in Post traumatic Clotted Hemothorax

Benha Medical Journal
Article 7, Volume 39, Issue 2, July and August 2022, Pages 409-417    PDF (467.82 K)
Document Type: Original Article
DOI: 10.21608/bmfj.2022.37822.1299
Authors
Mohammed Ahmed Elgazzar1; Hany Mohammed AlRakhawy2; Noha Metawaa* 3; Ashraf Mostafa Wahdan4; Mahmoud Ahmed Alshafiey5
1Lecturer of cardiothoracic surgery- Faculty of medicine -Benha University
2Professor of cardio thoracic surgery department- Faculty of medicine- Benha University
3Demonstrator of cardio thoracic surgery department-Faculty of medicine - Benha university
4Lecturer of cardio thoracic surgery- Faculty of medicine - Benha University
5Lecturer of cardio thoracic surgery- Faculty of medicine- Benha University
Abstract
Background: Post traumatic clotted hemothorax is a serious problem associated with fluid loculation by fibrous adhesions, trapped lungs and increase the risk of infection and empyema. Intrapleural instillation of streptokinase may dissolve fibrin clots and membranes, break down adhesions and facilitate complete evacuation of residual blood clots and loculated effusions especially if given in the 1st 7days post trauma.
The aim of this study is to evaluate the effect of streptokinase injection as a fibrinolytic drug treating patients with clotted hemothorax within and after 1-week post trauma.
Methodology of this study included 60 patients divided rondomly into 2 groups. Group A: include 30 patients with clotted hemothorax receiving streptokinase from 3rd to 7th day post trauma.
Group B: include 30 patients with clotted hemothorax receiving streptokinase after 1-week post trauma.
Results of this Stuy 4dy revealed no difference between both groups regarding age, gender, side of affection or number of SK injection doses. There were a significant reduction in surgical intervention post SK injection (P = 0.004), period between trauma and SK use (P < 0.001) and failure of SK injection (P = 0.002) and total hospital stay (P
Keywords
Clotted hemothorax; Intrapleural streptokinase injection; Time of chest trauma
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