Virulence of Entamoeba histolytica | ||
| Egyptian Academic Journal of Biological Sciences, E. Medical Entomology & Parasitology | ||
| Article 8, Volume 14, Issue 1, June 2022, Pages 87-100 PDF (698.47 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/eajbse.2022.234564 | ||
| Author | ||
| Al-Ahzzaa, Ghaida Rashid | ||
| Princess Nourh Bint Abdulrahman University, Science College, Biology department | ||
| Abstract | ||
| Entamoeba histolytica is an invasive protozoan, E. histolytica can adapt to the host’s gut environment due to the virulence of the parasite. Ca2+, Acetylcholine (ACh), Fe, and EhRho1 are believed to be important for parasite motility and adhesion. Cytolysis, phagocytosis, and microcytosis cause parasitic invasion. Amebiasis is treated with metronidazole (MTZ), although strains resistant to metronidazole have emerged. With the help of studying the virulence of the parasite, it was possible to search for other drugs. This review aims to present the key enzymes and the latest studies on promising drugs. | ||
| Keywords | ||
| Virulence; Entamoeba histolytic; Ca2+; Ach; EhGEF | ||
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