Synthesis, studying analytical properties and biological activity of new transition metal complexes with sulfadiazine derivative as reagent | ||
| Egyptian Journal of Chemistry | ||
| Volume 66, Issue 1, January 2023, Pages 55-61 PDF (801.96 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejchem.2022.104212.4814 | ||
| Authors | ||
| Ghusoon Jawad Abbas1; Zaied Mosaa2; Ali Jabbar Radhi* 3; Hayder Kadhim Abbas4; Walaa Mohammed Najem4 | ||
| 1Branch of Biochemistry, Faculty of Medicine,Jabir ibn Hayyan Medical University | ||
| 2College of science for women, University of Babylon, Hilla, Iraq. | ||
| 3Faculty of Pharmacy, Al-Kafeel University, Najaf, Iraq. | ||
| 4College of Pharmacy, University of Al-Kafeel, Najaf, Iraq. | ||
| Abstract | ||
| A new of nickel(II) and copper(II) complexes of 4-((4-acetylphenyl)diazenyl)-3-amino-N-(pyrimidin-2-yl) benzenesulfonamide (SDA) derived from sulfadiazine have been prepared and identified by FTIR, NMR, mass spectroscopy, UV-Visible spectroscopy, and elemental analysis. Also tested to evaluated their activities as antibacterial agents. The spectroscopic and analytical data suggest all prepared nickel(II) and copper(II) complexes a square planar geometry. The agar well diffusion method was used to test the target ligand and their Ni(II) and Cu(II) complexes for antibacterial activity against Gram (+) and Gram (-) bacteria. | ||
| Keywords | ||
| Antibacterial Activity; Sulfadiazine; Azo compound; Complexes | ||
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