A trial to improve the outcome of patients with cleft palate repair by using human fibrin glue: a study in 20 cases | ||
| The Egyptian Journal of Plastic and Reconstructive Surgery | ||
| Articles in Press, Accepted Manuscript, Available Online from 25 June 2022 | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejprs.2022.132638.1184 | ||
| Authors | ||
| mostafa fathy ibrahim* 1; Ahmad Mohamed Elsadat2; Seham Anwar Emam3 | ||
| 1plastic surgery beni suef university | ||
| 2Professor of General & Pediatric Surgery, Faculty of Medicine- Beni-Suef University, Egypt | ||
| 3Lecturer of General Surgery – Faculty of Medicine- Beni-Suef University, Egypt | ||
| Abstract | ||
| Introduction: Cleft palates are among the commonest craniofacial abnormalities. Cleft palate repair is not free of complications. The formation of a fistula is the most common complication of palatoplasty. Aim of work: To rectify the benefit of using human fibrin glue as a catalyst in primary palatoplasty and its effect on lowering the development of postoperative complications. Methods: primary palatoplasty was performed for twenty patients by double flap palatoplasty with human fibrin glue as a catalyst in the reform from January 2019 to June 2019. Fibrin glue was prepared from fresh frozen plasma to obtain thrombin and cryoprecipitate to obtain fibrinogen. Then was injected between the two palatal flaps and at the suture line as well Results: Out of twenty patients, 5 cases (25%) showed postoperative complications. Two cases (10%) were complicated by oronasal palatal fistula one of them (5%) were small (2mm) at the intersection of soft and hard palate without any nasal regurgitation and closed spontaneously within two months of postoperative follow-up. The other one(5%) continued for further surgical repair, and it also had early wound infection. Two cases(10%) were complicated by upper airway obstruction, and one patient (5%) was complicated by hemorrhage. Conclusions: The rate of occurrence of complications was less than in other studies that did the same procedure without the utilization of fibrin glue in the repair. More research with more patients and a more extended period of follow-up are recommended. | ||
| Keywords | ||
| cleft palate; repair; fibrin; glue; palatal fistula | ||
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