Khodeary, A., Mohamed, T., Alkhayat, K., Sayed, S. (2022). Bacterial Profile and Antibiotics Susceptibility Pattern of Pleural Effusion Isolates from Sohag University Hospital. test, 31(3), 29-35. doi: 10.21608/ejmm.2022.247177
Ashraf Khodeary; Tamer Mohamed; Khaled Alkhayat; Sherif Sayed. "Bacterial Profile and Antibiotics Susceptibility Pattern of Pleural Effusion Isolates from Sohag University Hospital". test, 31, 3, 2022, 29-35. doi: 10.21608/ejmm.2022.247177
Khodeary, A., Mohamed, T., Alkhayat, K., Sayed, S. (2022). 'Bacterial Profile and Antibiotics Susceptibility Pattern of Pleural Effusion Isolates from Sohag University Hospital', test, 31(3), pp. 29-35. doi: 10.21608/ejmm.2022.247177
Khodeary, A., Mohamed, T., Alkhayat, K., Sayed, S. Bacterial Profile and Antibiotics Susceptibility Pattern of Pleural Effusion Isolates from Sohag University Hospital. test, 2022; 31(3): 29-35. doi: 10.21608/ejmm.2022.247177

Bacterial Profile and Antibiotics Susceptibility Pattern of Pleural Effusion Isolates from Sohag University Hospital

Egyptian Journal of Medical Microbiology
Volume 31, Issue 3, July 2022, Pages 29-35    PDF (337.74 K)
Document Type: New and original researches in the field of Microbiology.
DOI: 10.21608/ejmm.2022.247177
Authors
Ashraf Khodeary1; Tamer Mohamed* 2; Khaled Alkhayat3; Sherif Sayed4
1Clinical Pathology Department, Faculty of Medicine, Sohag University, Egypt
2Medical Microbiology and Immunology department, Faculty of Medicine, Sohag University, Sohag , Egypt
3Chest Department, Faculty of Medicine, Sohag University, Egypt
4Lecturer, Clinical Pathology Department, Faculty of Medicine, Sohag University, Egypt
Abstract
Background: Diagnosis of pleural effusion (PE) infection and the isolated organisms reported a significant resistance to the commonly used antibiotics, and the choice of appropriate antibiotics for the management should be guided by microbiological results. Objectives: This study aimed to detect the bacterial profile and antibiotics susceptibility pattern of PE isolates and the prevalence of methicillin-resistant Staph. aureus. Methodology: Plural fluid samples from 121 patients with PE infection were collected for microbiological identification and antibiotic sensitivity testing by Vitek 2 system, Staphylococcal aureus isolates were tested for MecA gene by RT-PCR.  Results: 47% of PE samples exhibited positive culture, the most encountered organisms were Staph. aureus (24.2%), Klebsiella pneumoniae (16.1%), Staph aureus had the highest sensitivity to Vancomycin and Linezolid (100%) and (40%) of Staph aureus had mecA gene. Conclusion: Bacteria isolated from PE exhibited increasing levels of antibiotic resistance that should be reflected in the choice of empirical antimicrobial treatment.
Keywords
Bacterial isolates; Antibiotic resistance; Pleural Fluid
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