Characteristics of peripheral Leukocyte in moderate infection of COVID-19 | ||
| Journal of Bioscience and Applied Research | ||
| Volume 7, Issue 4, December 2021, Pages 216-222 PDF (769.19 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/jbaar.2021.251237 | ||
| Author | ||
| Ahmed Abdelhalim Yameny* | ||
| Society of Pathological Biochemistry and Hematology, Egypt | ||
| Abstract | ||
| Background: Blood leukocytes are an important part of the body’s defense system, and infection status can be predicted by measuring WBC levels. COVID-19 may involve many organ systems in its host. Studies suggest that hematological profiles change during SARS-CoV-2 illness. Patients and methods: This study included 504 mild infected patients with confirmed COVID-19 infection, these study subjects were randomly selected irrespective of the age group and both genders were included, EDTA blood sample was collected for performing total and differential white blood cells (Diagon D-cell 60 hematology analyzer Europe-Diagon Ltd. Hungary). Results: The present study included patients aged from14 years to 75 years mean age was 44.5 ±30.5 who were confirmed to have Covid-19 based on real-time reverse transcription-polymerase chain reaction, female gender was more frequent (n=280, 55.6%) than Male gender (n=224, 44.4%). This study reveals normal total WBCs count in 320 patients (63.5%), neutrophilia with a sensitivity of 77.8%, and lymphopenia with a sensitivity of 73%. Conclusion: Neutrophilia has a sensitivity of 77.8% and lymphopenia has a sensitivity of 73% for diagnosis or prognosis of mild infection of COVID-19 patients (Outpatients and patients under home observation). | ||
| Keywords | ||
| COVID-19; WBCs; neutrophilia; lymphopenia; biomarker | ||
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