Role of Human Coronaviruses in Acute Respiratory Infections and Seroprevalence of Middle East Respiratory Syndrome Coronavirus in children | ||
| Egyptian Journal of Medical Microbiology | ||
| Volume 29, Issue 4, October 2020, Pages 65-73 PDF (422.46 K) | ||
| Document Type: New and original researches in the field of Microbiology. | ||
| DOI: 10.51429/EJMM29409 | ||
| Authors | ||
| Ghada A. Fahmy* 1; Dina M. Erfan1; Sondos M. Magdy2; Rania A. Hassan1 | ||
| 1Department of Medical Microbiology and Immunology, Faculty of Medicine-Ain Shams University | ||
| 2Department of Pediatrics, Faculty of Medicine-Ain Shams University | ||
| Abstract | ||
| Background: Coronaviruses have been the focus of many studies since the emergence of SARS-CoV. Data on the role of MERS-CoV in respiratory tract infection and the seroprevalence of MERS-CoV in Egypt are limited. Objective: This study aimed to determine the role of coronaviruses in respiratory tract infections and the seroprevalence of MERS-CoV in pediatric age group. Methodology: Respiratory samples were collected from 80 children with respiratory infections for detection of coronaviruses using PCR technique. Serum samples were collected from 200 children for detection of MERS-CoV IgG immunolglobulins. Results: 4 out of 80 (5%) of the respiratory samples tested positive for coronavirus (OC43 subtype). None of respiratory samples tested positive for MERS-CoV, while MERS-CoV IgG was detected in 1% of serum samples.Conclusion: A low prevalence of coronaviruses was observed in children with respiratory infection. A seroprevalence of 1% MERS-CoV was detected. Further studies are recommended on larger scale. | ||
| Keywords | ||
| Coronaviruses; MERS-CoV; viral respiratory infection | ||
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