BIOLOGICAL EFFECT OF HIGH DIETARY FATS AND SUCROSE LEVEL ON LIVER FUNCTIONS AND LIPIDS PROFILE IN THE EXPERIMENTAL RATS | ||
| Journal of Soil Sciences and Agricultural Engineering | ||
| Article 8, Volume 28, Issue 7, July 2003, Pages 5815-5823 PDF (1.22 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/jssae.2003.252687 | ||
| Authors | ||
| Sh. Y. Kerolles,; W. A. EI Malky | ||
| National Organization for Drug Control and Research-Cairo, Egypt. | ||
| Abstract | ||
| The effect of a diet containing 25% edible fats (balady butler,balady samna. and hydrogenated fat); edible oils (corn oil, sunflower oil and mixed oil) and a diet containing 45% sucrose on body weight gain; organs weight (liver, kidney and splelen); liver enzymes (AL T and AST); lipid profile (Triglycerides, Total cholesterol (T.ch.), High density lipoprotein cholesterol (HDL-Ch), Low density Iipoprotein(LDL-Ch) and Total protein (TP). T he risk ratio is the result 0 f T .ch divided by H DL-ch were studied in the experimental rats. The feeding experimental was carried out during 45 days and the results were compared with control group of rats fed a balanced diet. The results showed that groups of rats fed on diet containing (25% edible fat and/or 45% sucrose) caused significant increase in body weight gain, organs weight, level of liver enzymes and lipid profiles of serum and liver extract, while slightly decreased in total protein was observed when compared with control. On the other side, data showed that no changes were observed for groups of rats fed on 25% edible oils on body weight gain, organs weight, liver enzymes, lipids profile and total protein comparing with control. While, the tow-tat (5%) group in rats diet yielded a significant decrease in the all previously parameters than control. this is due to the low fat content in the feeding diets of rats. In conclusion, although 25% edible oils was high fat diet. but it was less harmful effect on the liver functions and lipids profile than that recorded for the 25% edible fats (Saturated fatly acids) and thus it can be represented the 25% edible oils (unsaturated fatty acids) was healthy diet for the experimental rats. | ||
| Keywords | ||
| Lipid profile; High fat diet; High sucrose diet; Liver enzymes; AST and ALT | ||
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