ANTERIOR SEGMENT OPTICAL COHERENCE TOMOGRAPHY STUDY OF THE ANTERIOR OCULAR SURFACE IN THYROID EYE DISEASES | ||
| Egyptian Journal of Clinical Ophthalmology | ||
| Article 3, Volume 5, Issue 1, June 2022, Pages 19-28 PDF (571.61 K) | ||
| Document Type: Original articles: include clinical trials, interventional research, Basic researches and clinically relevant laboratory investigations | ||
| DOI: 10.21608/ejco.2022.252797 | ||
| Authors | ||
| Anwar, A.1; Mahmoud, M.1; Hassan, H.2; Ahmed, A.1 | ||
| 1Ophthalmology dept., Faculty of Medicine, Minia Univ., Egypt | ||
| 2Internal Medicine dept., Faculty of Medicine, Minia Univ., Egypt | ||
| Abstract | ||
| Purpose: Use the anterior segment optical coherence tomography (AS-OCT) to evaluate the tear meniscus parameters, total corneal thickness (CT), and epithelial thickness in active and inactive thyroid eye disease (TED) patients and compare them with age-matched controls. Patients and methods: This is a prospective case-control clinical study in which the subjects were divided into three groups, group I of inactive thyroid patients, group II of active thyroid patients, and group III of healthy controls. The AS-OCT was used to measure lower tear meniscus parameters (tear meniscus height (TMH), tear meniscus depth (TMD), and tear meniscus area (TMA)), total CT, and epithelial thickness. Results: All tear meniscus parameters (TMH, TMD, and TMA) were reduced in groups I and II with more reduction in group II with no significant difference between them with a significant difference when comparing groups I and II with group < br />III. The mean total CT was 496.7±19.9 in group I, 497.8±20.6 in group II, and 520.3±23.9 in group III with no significant difference (p-value = 0.757) between groups I and II while there was a significant difference when compared with healthy controls. The mean epithelial thickness was 46.5±2.6 in group I, 47.3±2.7 in group II, and 53.2±4.5 in group III with no significant difference between groups I and II while there was a significant difference when compared with healthy control. Conclusion: TED patients had reduced tear film parameters regardless of the thyroid activity, also the total CT and epithelial thickness was thinner in comparison with healthy controls. | ||
| Keywords | ||
| Anterior Segment Optical Coherence Tomography; Thyroid eye diseases-tear film | ||
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