The effect of Insulin and Metformin on Prevalence and Severity of Tooth Wear in type2 Diabetic Patients. | ||
| Egyptian Dental Journal | ||
| Article 20, Volume 68, Issue 3 - Serial Number 4, July 2022, Pages 2659-2667 PDF (343.42 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/edj.2022.133026.2070 | ||
| Authors | ||
| Abeer Younes* 1; Ahmed Hamam2 | ||
| 1Fixed Prosthodontics Department, Faculty of Dentistry,Tanta University. | ||
| 2Endocrinology and Metabolism Department, Armed Forces College of Medicine | ||
| Abstract | ||
| Purpose: investigating the effect of insulin and metformin on the prevalence and severity of tooth wear in patients with type 2 diabetes. Patients and methods: this cross sectional study was conducted on194 Egyptian adult diabetic type 2 patients, age group (50-70) using quota sampling method, assessing the prevalence and severity of tooth wear in adults of the included region. Three-stage stratification was done by sex, age and type of diabetes, then classified in to two groups: Group A: 105 patients treated with insulin regimens without metformin and stop metformin at least 5 years ago. Group B: 89 patients treated with metformin only. Measuring the tooth wear by Smith and Knight Tooth Wear Index (TWI). Results: Teeth Wear index (TWI) was significantly positively correlated to age and duration of diabetes in all groups. Treatment with metformin was a significant positive predictor of TWI. TWI was 1.857 higher on average for those who use metformin as compared to those who use insulin. Conclusion: There was a significant difference between different TWI as regard age and duration of diabetes. Any factor changes the oral salivary PH and viscosity will affect on the tooth wear severity. Keywords: type2 diabetes, tooth wear, insulin, metformin, tooth wear index | ||
| Keywords | ||
| type2 diabetes; tooth wear; insulin; metformin; tooth wear index | ||
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