Prevalence of antithyroid antibodies in patients with unexplained infertility | ||
| The Egyptian Journal of Fertility and Sterility | ||
| Article 8, Volume 16, Issue 1 - Serial Number 11106352, January 2012, Pages 27-29 PDF (940.92 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/egyfs.2012.257284 | ||
| Author | ||
| Maged ragheb Elshamy, Hosam Z Elhafez | ||
| Assistant professor of Obstetric and Gynecology, Obstetric and Gynecology Department, Mansoura University Hospital, Mansoura, EGYPT | ||
| Abstract | ||
| Objective: To evaluate the relative prevalence of antithyroid antibodies in unexplained infertility compared to other types of infertility. Patients and methods: The study comprised of 96 subfertile couples and 80 parous women attending outpatient clinic in Mansoura University Hospital. There were 30 patients had tubal causes, 16 patients had PCOS, 10 patients had endometriosis and 40 had unexplained infertility. Antithyroid auto-antibodies (antithyrglobulin and antimicrosomal) were estimated in the sera of all patients. Results: There were no significant differences in the frequency of antimicrosomal antibodies and antithyroglobulin in subfertile cases compared to the controls (25% and 22% versus 12% and 10%, P value 0.22 and 0.12, respectively). Subgroup analysis had revealed significantly higher frequency of women with positive antimicrosomal and antithyroglobulin antibodies in couples with unexplained infertility compared to fertile controls. Conclusion: A significantly higher proportion of thyroid auto-antibodies existed in women with unexplained subfertility compared to the fertile women. | ||
| Keywords | ||
| Key words: Subfertility; thyroid antibodies; unexplained infertility | ||
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