Mohamed, A., Yasin Mohamed, A. (2022). Efficacy Of High Flow Nasal Cannula Oxygenation In Acute Respiratory Failure Patients And Comparing With Noninvasive Positive Pressure Ventilation. test, 3(4), 65-71. doi: 10.21608/ejmr.2022.266288
Ahmed Shaban Ali Mohamed; Ahmed Yasin Mohamed. "Efficacy Of High Flow Nasal Cannula Oxygenation In Acute Respiratory Failure Patients And Comparing With Noninvasive Positive Pressure Ventilation". test, 3, 4, 2022, 65-71. doi: 10.21608/ejmr.2022.266288
Mohamed, A., Yasin Mohamed, A. (2022). 'Efficacy Of High Flow Nasal Cannula Oxygenation In Acute Respiratory Failure Patients And Comparing With Noninvasive Positive Pressure Ventilation', test, 3(4), pp. 65-71. doi: 10.21608/ejmr.2022.266288
Mohamed, A., Yasin Mohamed, A. Efficacy Of High Flow Nasal Cannula Oxygenation In Acute Respiratory Failure Patients And Comparing With Noninvasive Positive Pressure Ventilation. test, 2022; 3(4): 65-71. doi: 10.21608/ejmr.2022.266288

Efficacy Of High Flow Nasal Cannula Oxygenation In Acute Respiratory Failure Patients And Comparing With Noninvasive Positive Pressure Ventilation

Egyptian Journal of Medical Research
Volume 3, Issue 4, October 2022, Pages 65-71    PDF (352.01 K)
Document Type: Original Article
DOI: 10.21608/ejmr.2022.266288
Authors
Ahmed Shaban Ali Mohamed; Ahmed Yasin Mohamed
Critical care department, Faculty of Medicine, Beni-Suef University, Egypt
Abstract
The goal of this study is to assess HFNC oxygenation and compare the efficacy of high-flow nasal cannula (HFNC) to noninvasive ventilation (NIV) on oxygenation in patients with acute hypoxemic respiratory failure. The patients were randomly grouped into two groups, 20 in each group. Group 1: treated by high-flow nasal cannula (HFNC) and group 2: treated by non-invasive ventilation. There was a statistically significant difference regarding PaO2/FiO2 at baseline and at the end (P-value < 0.001) in both groups indicating improvement of oxygenation in both groups. There was a statistically significant difference between the two groups regarding the PaO2 and PaO2/FiO2 ratio (P-value < 0.05) at the end of the trial however the degree of oxygenation improvement was significantly higher with NIV group. The conclusion of our study: the use of high flow nasal cannula is effective in improving oxygenation but NIV was superior to HFNC.
Keywords
High flow nasal cannula; noninvasive ventilation; acute hypoxemic respiratory failure
References
  1. Avdeev, S. N. (2012). Current guidelines for oxygen therapy in emergency care. Terapevticheskii arkhiv, 84(12), 108-114.
  2. Buckley, T., Dudley, J., Eberhart, M., Goldstein, M., & Kallstrom, T. (2007). AARC clinical practice guideline: Oxygen therapy in the home or alternate site health care facility-2007 revision & update. Respiratory care, 52(8), 1063-1068.
  3. Driscoll, B. R., L. S. Howard, J. Earis and V. Mak (2017). "BTS guideline for oxygen use in adults in healthcare and emergency settings." Thorax 72(Suppl 1): ii1.
  4. Soni, N. and P. Williams (2008). "Positive pressure ventilation: what is the real cost?" BJA: British Journal of Anaesthesia 101(4): 446-457.
  5. Nava, S., & Hill, N. (2009). Non-invasive ventilation in acute respiratory failure. The Lancet, 374(9685), 250-259.
  6. Berg, K. M., Clardy, P., & Donnino, M. W. (2012). Noninvasive ventilation for acute respiratory failure: a review of the literature and current guidelines. Internal and emergency medicine, 7(6), 539-545.
  7. Esteban, A., Ferguson, N. D., Meade, M. O., Frutos-Vivar, F., Apezteguia, C., Brochard, L., ... & Anzueto, A. (2008). Evolution of mechanical ventilation in response to clinical research. American journal of respiratory and critical care medicine, 177(2), 170-177.
  8. Lee, C. C., Mankodi, D., Shaharyar, S., Ravindranathan, S., Danckers, M., Herscovici, P., ... & Ferrer, G. (2016). High flow nasal cannula versus conventional oxygen therapy and non-invasive ventilation in adults with acute hypoxemic respiratory failure: a systematic review. Respiratory medicine, 121, 100-108.
  9. Vargas, F., Saint-Leger, M., Boyer, A., Bui, N. H., & Hilbert, G. (2015). Physiologic effects of high-flow nasal cannula oxygen in critical care subjects. Respiratory care 60(10): 1369-1376.
  10. Schwabbauer, N., Berg, B., Blumenstock, G., Haap, M., Hetzel, J., & Riessen, R. (2014). Nasal high–flow oxygen therapy in patients with hypoxic respiratory failure: effect on functional and subjective respiratory parameters compared to conventional oxygen therapy and non-invasive ventilation (NIV). BMC anesthesiology, 14(1), 1-7.
  11. Stéphan, F., Barrucand, B., Petit, P., Rézaiguia-Delclaux, S., Médard, A., Delannoy, B., ... & BiPOP Study Group. (2015). High-flow nasal oxygen vs noninvasive positive airway pressure in hypoxemic patients after cardiothoracic surgery: a randomized clinical trial. Jama, 313(23), 2331-2339.
  12. Liesching, T. N., & Lei, Y. (2019). Efficacy of high-flow nasal cannula therapy in intensive care units: a meta-analysis of physiological and clinical outcomes. Journal of intensive care medicine, 34(2), 140-152.
  13. Frat, J. P., Brugiere, B., Ragot, S., Chatellier, D., Veinstein, A., Goudet, V., ... & Girault, C. (2015). Sequential application of oxygen therapy via high-flow nasal cannula and noninvasive ventilation in acute respiratory failure: an observational pilot study. Respiratory care, 60(2), 170-178.
  14. Simon, M., Braune, S., Frings, D., Wiontzek, A. K., Klose, H., & Kluge, S. (2014). High-flow nasal cannula oxygen versus non-invasive ventilation in patients with acute hypoxaemic respiratory failure undergoing flexible bronchoscopy-a prospective randomised trial. Critical Care, 18(6), 1-9.
Statistics
Article View: 271
PDF Download: 239