Current Development in Peptide Surrogates Synthesis and Their Biological Applications | ||
| Egyptian Journal of Chemistry | ||
| Volume 66, Issue 8, August 2023, Pages 251-267 PDF (925.49 K) | ||
| Document Type: Review Articles | ||
| DOI: 10.21608/ejchem.2022.159709.6887 | ||
| Authors | ||
| Atef Kalmouch1; Ahmed M. Naglah1; Gaber O. Moustafa* 2 | ||
| 1Peptide Chemistry Department, Chemical Industries Research Division, National Research Centre, 12622- Dokki, Cairo, Egypt | ||
| 2Peptide Chemistry Department, Chemical Industries Research Division, National Research Centre, 12622-Dokki, Cairo, Egypt. | ||
| Abstract | ||
| Many new peptide therapeutics are increasingly making their way to rapid and successful clinical application. In fact, some naturally derived peptide chains were used as effective drugs for several years. With the emergence of very large libraries of peptides with high biological properties, it is expected that several potential candidates will be introduced to the list of under-development peptides, introducing new drug-administration strategies derived from polypeptide chains and improvements in the purification half-life in vivo. Despite remaining potential hurdles, peptide therapies are poised to play an important role in treating diseases ranging from Alzheimer's disease to cancer. | ||
| Keywords | ||
| Amino Acid and Peptides; Biological Applications; Anticancers; Antimicrobials; Alzheimer' s disease; Malaria | ||
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