Tawfik, N., Romeia, S., Youssef, N., Atwa, M. (2022). Mean Platelet Volume in Psoriasis: Is it a New Prognostic Indicator?. test, 25(4), 54-60. doi: 10.21608/scumj.2022.270509
Noha Tawfik; Samar GA Romeia; Nahed Youssef; Mona A. Atwa. "Mean Platelet Volume in Psoriasis: Is it a New Prognostic Indicator?". test, 25, 4, 2022, 54-60. doi: 10.21608/scumj.2022.270509
Tawfik, N., Romeia, S., Youssef, N., Atwa, M. (2022). 'Mean Platelet Volume in Psoriasis: Is it a New Prognostic Indicator?', test, 25(4), pp. 54-60. doi: 10.21608/scumj.2022.270509
Tawfik, N., Romeia, S., Youssef, N., Atwa, M. Mean Platelet Volume in Psoriasis: Is it a New Prognostic Indicator?. test, 2022; 25(4): 54-60. doi: 10.21608/scumj.2022.270509

Mean Platelet Volume in Psoriasis: Is it a New Prognostic Indicator?

Suez Canal University Medical Journal
Article 7, Volume 25, Issue 4, December 2022, Pages 54-60    PDF (350.81 K)
Document Type: Original Article
DOI: 10.21608/scumj.2022.270509
Authors
Noha Tawfik* 1; Samar GA Romeia1; Nahed Youssef2; Mona A. Atwa1
1Department of Dermatology, Venereology, and Andrology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.
2Department of Clinical Pathology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt
Abstract
Background: Psoriasis is a chronic multifactorial inflammatory autoimmune disease. It has significant impacts on health and quality of life. Platelets play a major role in the pathogenesis of psoriasis, and the activated platelets increase the migration of leukocytes to the skin, increasing the release of inflammatory cytokines. Recent studies showed that MPV (mean platelet volume) could be used as an indicator of platelet function and activation. Previous studies assessed only the value of MPV in psoriatic patients without studying its relationrelationship < /ins> with different treatment modalities. Aim:To study the changes in MPV in psoriasis patients and its association with disease severity after treatment with NB-UVB. Patents and Methods: 25 psoriatic patients were assessed for MPV and psoriasis area and severity index score (PASI) before treatment, during treatment and after treatment with NBUVB (three times weekly for 3 months). Results:The relation between MPV and PASI was statistically insignificant before and after treatment. The PASI score was significantly decreases after treatment. Conclusion: This study demonstrated insignificant correlation between MPV levels and PASI score of psoriatic patients before and after NBUVB phototherapy. Further studies on larger number of patients were needed to assess the relation between MPV and psoriasis.
 
Keywords
Psoriasis; Mean Platelet Volume; NB-UVB
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