Benmoussa, M., Nadji, S., Boudjemaa, S., Bounab, A., Hadef, Y. (2022). EVALUATION OF BIOLOGICAL ACTIVITIES OF MATRICARIA PUBESCENS FROM ALGERIA. test, 45(2), 723-736. doi: 10.21608/bfsa.2022.271595
Mohamed taher Benmoussa; Said Nadji; Soumaya Boudjemaa; Abdelhakim Bounab; Youcef Hadef. "EVALUATION OF BIOLOGICAL ACTIVITIES OF MATRICARIA PUBESCENS FROM ALGERIA". test, 45, 2, 2022, 723-736. doi: 10.21608/bfsa.2022.271595
Benmoussa, M., Nadji, S., Boudjemaa, S., Bounab, A., Hadef, Y. (2022). 'EVALUATION OF BIOLOGICAL ACTIVITIES OF MATRICARIA PUBESCENS FROM ALGERIA', test, 45(2), pp. 723-736. doi: 10.21608/bfsa.2022.271595
Benmoussa, M., Nadji, S., Boudjemaa, S., Bounab, A., Hadef, Y. EVALUATION OF BIOLOGICAL ACTIVITIES OF MATRICARIA PUBESCENS FROM ALGERIA. test, 2022; 45(2): 723-736. doi: 10.21608/bfsa.2022.271595

EVALUATION OF BIOLOGICAL ACTIVITIES OF MATRICARIA PUBESCENS FROM ALGERIA

Bulletin of Pharmaceutical Sciences Assiut University
Volume 45, Issue 2, December 2022, Pages 723-736    PDF (869.23 K)
Document Type: Original Article
DOI: 10.21608/bfsa.2022.271595
Authors
Mohamed taher Benmoussa* 1; Said Nadji2; Soumaya Boudjemaa3; Abdelhakim Bounab4; Youcef Hadef5
1Department of pharmacy, University of Batna2
2Laboratory of Toxicology, University hospital of Batna,
3Laboratory of Toxicology, University hospital of Batna
4Laboratory of mineral chemistry, Faculty of pharmacy, University of Algiers
5Laboratory of Analytical chemistry, Department of pharmacy, Faculty of Medicine, University of Annaba
Abstract
Abstract: Matricaria pubescens is a plant of the asteraceae family that grows wild in Algeria and throughout North Africa especially in the desert. It is commonly used as folk medicine to cure a variety of ailments in various preparations, aerial parts of the plant were sampled from two different sites in Algeria, the biological activities of the methanolic extracts and essential oils have been evaluated namely  antioxidant, anti-inflammatory, antidiabetic, antibacterial, and antifungal activities, besides a safety bioassay ,  The essential oils of the plant have shown significant efficacy against the studied bacteria, and a strong antifungal activity against Candida albicans. Methanolic extracts and essential oils have shown noticeable anti-inflammatory activity. The essential oils showed good antidiabetic activity and weak antioxidant power. Meanwhile Matricaria pubecens essential oils noted significant cytolytic effect that may hamper its systemic use, it also noteworthy to mention the variability between the samples confirming the differences in the chemical patterns.
Keywords
Essential oil; Methanolic extracts; Biological activities; Matricaria pubescens; toxicity
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