Biomedical Applications and Toxicological Aspects of Zinc Oxide Nanoparticles: A Review Article | ||
| Sohag Medical Journal | ||
| Volume 27, Issue 1., 2023, Pages 18-27 PDF (651.01 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/smj.2022.173745.1354 | ||
| Authors | ||
| Hend Gamal Aref* 1; Ahmed Mohamed Said2; Eman Khalifa Ahmed3; Mai Mostafa AbdelKader4; Aya Magdy Elkady5; Soheir Ali Mohamed6 | ||
| 1Forensic medicine and Clinical toxicology department , faculty of medicine , Sohag University , Egypt. | ||
| 2forensic medicine and clinical toxicology depart, faculty of medicine, sohag university, sohag, egypt | ||
| 3Histology Department , Faculty of Medicine, Sohag University, Sohag, Egypt. | ||
| 4forensic medicine and clinical toxicology department, faculty of medicine, sohag university,egypt | ||
| 5Forensic medicine and clinical toxicology department, Faculty of medicine, Sohag university, Eygpt. | ||
| 6Department of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, sohag University, Sohag, Egypt | ||
| Abstract | ||
| Nanotechnology is one of the fastest-growing and most promising modern technologies. It deals with the manufacturing and use of nanoparticles. Nanoparticles are generally known as small-sized particles possessing a size range of 1 to 100 nm. Due to their distinctive physicochemical and mechanical characteristics, they are utilized in various fields like agriculture, material science, food industry, medical, diagnostic, and cosmetic applications. One of the nanoparticles that is most frequently used nowadays is Zinc oxide nanoparticles. They have been explored for numerous biomedical applications, such as drug delivery, anticancer, antibacterial, antidiabetic, and bioimaging. Researchers expect that usage of Zinc oxide nanoparticles will expand so; the human body's exposure to them will increase. Zinc oxide .nanoparticles released into the environment could lead to adverse human and animal health effects. Recent studies concluded that Zinc oxide nanoparticles could cross some blood vital organs barriers and cell membranes, generate free radicals, and exhibit oxidative stress, cytotoxicity, and genotoxicity. Therefore, great attention must be taken to assess the toxicological aspects of nanoparticles. | ||
| Keywords | ||
| Nanotechnology; Zinc oxide nanoparticles; Biomedical applications; Toxicity | ||
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