Hemodynamic Changes during Sepsis among Pediatrics: Review Article | ||
| The Egyptian Journal of Hospital Medicine | ||
| Article 237, Volume 89, Issue 2, October 2022, Pages 7696-7700 PDF (336.37 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejhm.2022.276903 | ||
| Authors | ||
| Aya Elewa Abdelhamid; Mohammed Mahmoud Romih; Alaa Elsayed Nafae | ||
| Abstract | ||
| Background: Peripheral dilatation and shunting between arteries and capillaries characterize the circulatory maldistribution known as septic distributive shock. Yet, there are both hyperdynamic (warm) and hypodynamic (cool) forms of septic shock. Objective: The aim of the current study is to assess the hemodynamic changes during sepsis among pediatric population. Methodology: We searched PubMed, Science Direct and Google Scholar for information on “Hemodynamic Changes with Sepsis”. However, only the most current or comprehensive study from January 2010 to May 2022 was considered. The authors also assessed references from pertinent literature. Documents in languages other than English have been disregarded since there aren't enough resources for translation. Unpublished manuscripts, oral presentations, conference abstracts, and dissertations were examples of papers that weren't considered to be serious scientific research. Results: Despite a high Left ventricular ejection fraction (LVEF; typically >55%), stroke volume is reduced in the early stages of sepsis due to inadequate cardiac preload brought on by increased vascular permeability and vasodilation. Even though left ventricular (LV) systolic dysfunction is common in septic patients, it may be reversible in survivors. Those who die from sepsis have a lower left ventricular end-diastolic volume (LVEDV) than those who do, even if they receive more fluids than those who do later in the disease. Conclusion: Our result is in keeping with the hypothesis of a continuing preload deficit. Some studies have found an association between sepsis and cardiac depression, with survivors having a higher prevalence of cardiac depression than no survivors. | ||
| Keywords | ||
| Sepsis; Hemodynamic changes; Left ventricular end-diastolic volume | ||
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