Adli, D., Ziani, K., Kourat, D., Brahmi, M., Souidi, S., Naar, A., Kahloula, K., Slimani, M. (2022). Ameliorative Effect of The Essential Oil of Syzygium aromaticum in Wistars Rats Exposed to Aluminum Chloride. test, 14(2), 403-413. doi: 10.21608/eajbsc.2022.277234
Djallal Eddine Houari Adli; Kaddour Ziani; Dallal Kourat; Mostapha Brahmi; Sendous Adjila Souidi; Asma Naar; Khaled Kahloula; Miloud Slimani. "Ameliorative Effect of The Essential Oil of Syzygium aromaticum in Wistars Rats Exposed to Aluminum Chloride". test, 14, 2, 2022, 403-413. doi: 10.21608/eajbsc.2022.277234
Adli, D., Ziani, K., Kourat, D., Brahmi, M., Souidi, S., Naar, A., Kahloula, K., Slimani, M. (2022). 'Ameliorative Effect of The Essential Oil of Syzygium aromaticum in Wistars Rats Exposed to Aluminum Chloride', test, 14(2), pp. 403-413. doi: 10.21608/eajbsc.2022.277234
Adli, D., Ziani, K., Kourat, D., Brahmi, M., Souidi, S., Naar, A., Kahloula, K., Slimani, M. Ameliorative Effect of The Essential Oil of Syzygium aromaticum in Wistars Rats Exposed to Aluminum Chloride. test, 2022; 14(2): 403-413. doi: 10.21608/eajbsc.2022.277234

Ameliorative Effect of The Essential Oil of Syzygium aromaticum in Wistars Rats Exposed to Aluminum Chloride

Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology
Volume 14, Issue 2, December 2022, Pages 403-413    PDF (575.11 K)
Document Type: Original Article
DOI: 10.21608/eajbsc.2022.277234
Authors
Djallal Eddine Houari Adli1; Kaddour Ziani1; Dallal Kourat1; Mostapha Brahmi2; Sendous Adjila Souidi1; Asma Naar1; Khaled Kahloula1; Miloud Slimani1
1Laboratory of Biotoxicology, Pharmacognosy and Biological Valorization of plants (LBPVBP), Department of Biology, Faculty of Sciences, University of Dr Moulay Tahar, Saida, Algeria
2Laboratory of Biotoxicology, Pharmacognosy and Biological Valorization of plants (LBPVBP), Department of Biology, Faculty of Sciences, University of Dr Moulay Tahar, Saida, Algeria-Department of Biology, Faculty of Science and Technology, University of Relizane 48000, Algeria
Abstract
The objective of this study, on the one hand, is to evaluate the impact of aluminium intoxication, on the biochemical and hematological approaches of adult Wistar rats, on the other hand, to test the efficacy of Syzygium aromaticum essential oil (CEO) in restoring or not the harmful effects of the studied metal with a daily intraperitoneal injection of 0.1 ml CEO/kg. The extraction of the essential oil from S.aromaticum by hydro-distillation allowed us to obtain CEO with a yield of 10.18%. Chronic exposure to aluminum chloride at a concentration of 100mg/kg in rats decreased body and organ weights (Liver, Kidney) compared to controls. The intoxication also revealed a disruption of various biochemical parameters, including liver (TGO, TGP), and kidney (urea, creatinine) biochemical assays, Thus, the concentration of aluminium in the intoxicated group is high in the blood. Also, the results show a correction in the values of these parameters following the administration of CEO compared to those of exposed animals. CEO also corrected the shape of the affected blood cells after intoxication to aluminium. 
Keywords
Syzygium aromaticum; aluminiumcloride; Kidney; Liver; Blood
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