Chronic Obstructive Pulmonary Disease: Pathogenesis and advanced treatment | ||
| Sohag Medical Journal | ||
| Volume 27, Issue 1, 2023, Pages 21-25 PDF (752.18 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/smj.2023.173669.1353 | ||
| Authors | ||
| Ebtisam Mohammed Gad* 1; Doaa Mohamed Gad2; Sara Mostafa Sleem3; Zeinab Mahmoud Kadry4; Enas Khalifa Ahmed Abuzied5 | ||
| 1Chest Diseases and Tuberculosis Department, faculty of Medicine, Sohag University | ||
| 2Ent department .faculty of medicine,Sohag university | ||
| 3Otorhinolarynglogy department, Sohag faculty of medicine, sohag university, sohag, Egypt. | ||
| 4Department of Medical Biochemistry, Faculty of Medicine Sohag University | ||
| 5department of Chest diseases and Tuberculosis,Faculty of medicine,Sohag University Hospital,Sohag | ||
| Abstract | ||
| Chronic obstructive pulmonary disease (COPD) is a common and heterogeneous disorder. The current treatment of COPD is restricted to the use of bronchodilators like β2 agonists and anticholinergic and anti-inflammatory drugs like corticosteroids. This requires a significant increase in the therapeutic options available for COPD that is closely related to the widening of knowledge on the underlying mechanisms of the disease. The great interest in the development of novel drugs that can interfere with the natural history of COPD leads to the synthesis of numerous novel molecules that will target these inflammatory pathways. Key Words: COPD – emerging therapy - anti-inflammatory - bronchodilator – cytokine – chemokine. Background: COPD is a major global health problem. COPD is a preventable and treatable disease. This, in part, reflects a better understanding of the molecular mechanisms of COPD and the development of novel therapies that can improve the health outcomes of COPD patients. | ||
| Keywords | ||
| antiinflammatory; cytokines; chemokines | ||
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