Synthesis of Fluconazole and its ionic liquid derivatives, and evaluation of their ability to prevent carbon steel corrosion in hydrochloric acid solution | ||
| Egyptian Journal of Chemistry | ||
| Volume 66, Issue 9, September 2023, Pages 263-269 PDF (1.73 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejchem.2023.180238.7318 | ||
| Authors | ||
| M.A. Deyab* 1; Abdelfattah haikal2; Abdalla E. A. Hassan2; Azza El-Kafrawy2; N.A. Khalil1; Medhat R. Hussein2 | ||
| 1Egyptian Petroleum Research Institute (EPRI), Nasr City, Cairo, Egypt | ||
| 2Chemistry Department, Faculty of Science, Zagazig University, Zagazig, Egypt | ||
| Abstract | ||
| Fluconazole, an antifungal drug, and its ionic liquid derivatives were successfully prepared and evaluated for corrosion suppression on carbon steel in hydrochloric acid solution using electrochemistry estimations. The chemical configuration and characterizations of fluconazolium ionic liquids were verified using FT-IR and nuclear magnetic resonance (1H NMR, 13C NMR). The results demonstrate that the above additives perform as inhibitors in acidic corrosive environments and exhibit a strong trend in which inhibition capability increased with increasing inhibitor dose. At 100 ppm, polarization data revealed that fluconazole and fluconazolium ionic liquids had relatively high inhibition capacity (91.26, 98.77, and 98.03%). Fluconazole and its identified ionic liquid derivatives accumulated on the surface of carbon steel using the Langmuir adsorption isotherm concept. | ||
| Keywords | ||
| Fluconazole; ionic liquid; steel; corrosion; electrochemistry | ||
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