Mohammed, N., Maged, D., Abo seif, A., Maghraby, H. (2023). Cerebroplacental doppler ratio in prediction of adverse perinatal outcome in term normal pregnancy. test, 4(1), 47-54. doi: 10.21608/jram.2023.144442.1172
Nabila A. Mohammed; Diaa MM. Maged; Amal H. Abo seif; Hala M. Maghraby. "Cerebroplacental doppler ratio in prediction of adverse perinatal outcome in term normal pregnancy". test, 4, 1, 2023, 47-54. doi: 10.21608/jram.2023.144442.1172
Mohammed, N., Maged, D., Abo seif, A., Maghraby, H. (2023). 'Cerebroplacental doppler ratio in prediction of adverse perinatal outcome in term normal pregnancy', test, 4(1), pp. 47-54. doi: 10.21608/jram.2023.144442.1172
Mohammed, N., Maged, D., Abo seif, A., Maghraby, H. Cerebroplacental doppler ratio in prediction of adverse perinatal outcome in term normal pregnancy. test, 2023; 4(1): 47-54. doi: 10.21608/jram.2023.144442.1172

Cerebroplacental doppler ratio in prediction of adverse perinatal outcome in term normal pregnancy

Journal of Recent Advances in Medicine
Article 7, Volume 4, Issue 1, January 2023, Pages 47-54    PDF (684.17 K)
Document Type: Original Article
DOI: 10.21608/jram.2023.144442.1172
Authors
Nabila A. Mohammed* 1; Diaa MM. Maged2; Amal H. Abo seif2; Hala M. Maghraby3
1Gynecology and Obstetrics Department, Elsinbelaween General Hospital, Elsinbelaween , Aldakahlia, Egypt.
2Gynecology and Obstetrics Department, Faculty of Medicine for Girls, Cairo, Al-Azhar University, Egypt.
3Radiodiagnosis Department, Faculty of Medicine for Girls, Cairo, Al-Azhar University, Egypt.
Abstract
Background: The cerebroplacental ratio (CPR) may be able to detect fetus that do not develops fully at term and predict poor pregnancy outcomes. In third-trimester studies of high-risk pregnancies, low CRP due to increased umbilical artery (UA) or fetus middle cerebral artery pulsatility index (MCA-PI) has been linked to poor pregnancy outcomes. .
Objective: To assess the predictive utility of doppler CPR for screening of full-term (37 week - 40 week) normal un-complicated pregnancies with a bad outcome.
Methodology: This observational hospital based cross sectional study was conducted on 500 women normal uncomplicated full-term pregnancy (37- 40 weeks),  giving birth at Al-Zahraa university hospital and Elsinbelaween general hospital from June 2021 to June 2022. All women were subjected to measurement of abdominal ultrasound, femur length (FL), abdominal circumference (AC), gestational age, complete, cardiotocography (CTG) to assess fetal, and umbilical and placental doppler for middle cerebral artery (MCA) and umbilical artery (UA).
Results: MCA systolic / diastolic (S/D) ratio was inversely correlated with pCO2, while UA-S/D ratio was  positively correlated with pCO2 and negatively correlated with all other parameters except neonatal death and neonatal intensive care unit admission.

Conclusion: In full-term normal pregnancy, the CPR is an excellent predictor of unfavorable perinatal outcome
Keywords
Cerebroplacental; doppler; fetal outcome; biomarkers
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