THE ROLE OF LOCAL ESTROGEN THERAPY IN POSTMENOPAUSAL OVERACTIVE BLADDER | ||
| ALEXMED ePosters | ||
| Article 1, Volume 5, Issue 1, January 2023, Pages 12-13 | ||
| Document Type: Preliminary preprint short reports of original research | ||
| DOI: 10.21608/alexpo.2023.187538.1547 | ||
| Authors | ||
| Wafaa Aboulenein1; Tamer Abd Aldayem2; Dina Hesham Abd El-Galil Elhedeny* 3 | ||
| 1Obstetrics and Gynecology Department, Faculty of Medicine, Alexandria University, Egypt | ||
| 2Obstetric and Gynecology department, faculty of Medicine, Alexandria University, Alexandria | ||
| 3Department of Obstetrics and Gynecology, Faculty of Medicine - Alexandria University | ||
| Abstract | ||
| Overactive bladder (OAB) is relatively common in the general population but more common in women, especially in postmenopausal women with the genitourinary syndrome of menopause (GSM). AIM OF THE WORK: The aim of this study was to assess the efficacy of local estrogen hormone in improving the OAB symptoms in postmenopausal women with GSM. PATIENTS AND METHODS: A randomized, double-blind, placebo-controlled was carried out on 56 patients with GSM with the complaints consistent with OAB and recruited from the urogynecology out-patient clinic, Department of obstetrics and gynecology at El Shatby Alexandria University Hospital. Patients were divided into two groups: Group (A) received 0.5 g of conjugated estrogen (Premarin vaginal cream) twice weekly for 8 weeks, and group (B) received a placebo at the same dose. All subjects were subjected to full history taking, questionnaire derived from the UDI-6 and IIQ-7, clinical examination and investigations including complete urine analysis and urodynamic studies. After 8 weeks, patients in both groups were assessed again by a UDI-6 and IIQ-7 and urodynamics, and the results of both groups were compared. | ||
| Keywords | ||
| Overactive bladder; ESTROGEN; postmenopausal women | ||
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