Effect of Phytoestrogen (Fennel) on Some Sex Hormones and Other Physiological Parameters in Male Albino Rats | ||
| The Egyptian Journal of Hospital Medicine | ||
| Article 21, Volume 74, Issue 7, January 2019, Pages 1616-1620 PDF (516.35 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejhm.2019.28268 | ||
| Authors | ||
| Eman G.E. Helal* 1; Nora Abdul-Aziz AL Jalaud2; Mohamed A. El-Aleem3; Shaimaa S. Ahmed1 | ||
| 1Zoology Department, Faculty of Science, Al-Azhar University (Girls), Cairo, Egypt | ||
| 2Imam Abdulrahman Bin Faisal University | ||
| 3Physiology Department, Faculty of Medicine, Al-Azhar University (Boys), Cairo, Egypt | ||
| Abstract | ||
| Background: Phytoesrogenis plant derived compounds which have an estrogenic effect. Objectives: The present study was carried out to investigate some pharmacological and biochemical effects of fennel oil on male albino rats. Materials and methods: Twelve animals were divided randomly into two groups. Group A: Control. Group B: Treated rats. The rats were given an oral dose of 1 ml/kg body weight/day fennel oil once daily for one month. At the end of the experiment, blood samples were collected for biochemical analysis. Results: The fennel oil induced highly significant decrease (p<0.01) in total cholesterol(TC), triglycerides (TG), low-density lipoprotein (LDL), very low-density lipoprotein (VLDL), LDL/high-density lipoprotein (HDL), while significant increased (p<0.05) HDL. In addition, it showed highly significant decrease (p<0.02) in FSH, testosterone and sperm count compared to normal control group. Conclusion: Fennel herb has several therapeutic benefits, but it also has negative effect on male sex hormone and sperm count. So men must reduce their usage of it. | ||
|
Statistics Article View: 727 PDF Download: 5,353 |
||
