Khairallah, M., Sobh, M., Mansour, E., Ibrahim, R., Mostafa, M. (2023). Renal Resistive Index as a Promising Tool in Early Identification of Diabetic Nephropathy. test, 90(1), 1983-1987. doi: 10.21608/ejhm.2023.284774
Marwa K. Khairallah; Mohamed Abbas Sobh; Ehab Mansour; Radwa Ibrahim; Mohamed Hassan Mostafa. "Renal Resistive Index as a Promising Tool in Early Identification of Diabetic Nephropathy". test, 90, 1, 2023, 1983-1987. doi: 10.21608/ejhm.2023.284774
Khairallah, M., Sobh, M., Mansour, E., Ibrahim, R., Mostafa, M. (2023). 'Renal Resistive Index as a Promising Tool in Early Identification of Diabetic Nephropathy', test, 90(1), pp. 1983-1987. doi: 10.21608/ejhm.2023.284774
Khairallah, M., Sobh, M., Mansour, E., Ibrahim, R., Mostafa, M. Renal Resistive Index as a Promising Tool in Early Identification of Diabetic Nephropathy. test, 2023; 90(1): 1983-1987. doi: 10.21608/ejhm.2023.284774

Renal Resistive Index as a Promising Tool in Early Identification of Diabetic Nephropathy

The Egyptian Journal of Hospital Medicine
Article 296, Volume 90, Issue 1, January 2023, Pages 1983-1987    PDF (261.11 K)
Document Type: Original Article
DOI: 10.21608/ejhm.2023.284774
Authors
Marwa K. Khairallah; Mohamed Abbas Sobh; Ehab Mansour; Radwa Ibrahim; Mohamed Hassan Mostafa
Abstract
Background: Diabetes mellitus (DM) is a common chronic illness that affects many persons all over the world. Diabetic nephropathy (DN) is a common serious problem that occurs in a considerable percentage of diabetic patients. Renal resistive index (RI) reflects hemodynamics of intrarenal arteries.
Objective: Here, we aimed to determine efficacy of RI in prediction of DN.
Patients and methods: A cross-sectional study was conducted over one year duration in Nephrology Unit of Internal Medicine Department, Assiut University Hospital. A total of 91 patients with DM were recruited. All patients were evaluated based on history taking, clinical evaluation, laboratory data and renal RI and subdivided into DN group and non-DN group.
Results: Out of those patients; 40 (43.9%) patients had DN (DN group) and 51 (56.1%) patients hadn’t DN (No-DN group). Patients with DN had significantly longer duration of DM (10.45 ± 1.11 vs. 4.09 ± 0.56 (years); p < 0.001) and higher RI (0.89 ± 0.11 vs. 0.49 ± 0.18; p < /em>< 0.001). Duration of DM (> 5 years), impaired glycemic control and resistive index were predictors for DN among patients with DM. At cutoff point > 0.73, resistive index had 82.5% overall accuracy with area under curve was 0.837 for prediction of diabetic nephropathy.
Conclusion: Renal RI reflects hemodynamics of intrarenal arteries in patients with DM and could be used as a promising tool in early identification of DN. Multiple future studies at multiple centers with long term duration of assessment are warranted.
 
Keywords
Resistive index; Diabetic nephropathy; Diabetes mellitus; Accuracy
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