Effect of Propofol Fresensius 1% on nervous system ultrastructure of Biomphalaria alexandrina. | ||
| Egyptian Journal of Aquatic Biology and Fisheries | ||
| Article 22, Volume 23, Issue 1, January 2019, Pages 265-274 PDF (835.81 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejabf.2019.28517 | ||
| Authors | ||
| Hanan S. Mossalem; Shereen M. Mansour | ||
| Abstract | ||
| This study was aimed to evaluate the effect of propofol fresensius 1% on the nervous system of Biomphalaria alexandrina snails, which represent the intermediate host of schistosoma mansoni after acute exposure (5ml/L) for 24 hours and chronic exposure (1ml/L) for 72 h, using scanning and transmission electron microscope. After chronic exposure, visceral ganglion was observed compressed and elongated, not paired with pedal ganglia and its nerves did not contact with it. 1ml/L propofol completely blocked synaptogenesis between visceral and pedal neurons. After acute exposure, the varicosities have few granular vesicles, whereas in the chronic exposure, the varicosities were empty and no granular vesicles were found inside it. Poorly developed endoplasmic reticulum, few Golgi bodies, elongated mitochondria, and more intercellular connective space were observed. | ||
| Keywords | ||
| Propofol fresensius Nervous system; Biomphalaria alexandrina; Bioindicator; Golgi bodies | ||
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